Pavlova T V
Arkh Patol. 1986;48(6):40-4.
To investigate early stages of hypoxia, the authors studied fetal capillaries of the terminal cilia in the placenta of women without clinical manifestations of fetal hypoxia in such pathologic states as protracted labor, uterine fibromyoma, late toxicosis of pregnancy. The capillaries are shown to have the same typical changes: the increase of nuclear volume, of the number of cytoplasmic organellae (mitochondria, cysternae of the granular endoplasmic reticula, polysomes and free ribosomes, pinocytic vesicules) and cytoplasmic appendages, which come into active contact with the blood cells. These changes are directed to normalization of oxygen and nutrient supply to the fetus.
为了研究缺氧的早期阶段,作者对处于产程延长、子宫肌瘤、妊娠晚期中毒等病理状态下但无胎儿缺氧临床表现的孕妇胎盘终末纤毛的胎儿毛细血管进行了研究。结果显示,这些毛细血管呈现出相同的典型变化:核体积增大、细胞质细胞器(线粒体、颗粒内质网池、多核糖体和游离核糖体、吞饮小泡)数量增加以及细胞质附属物增多,且这些附属物与血细胞发生活跃接触。这些变化旨在使胎儿的氧气和营养供应恢复正常。