[Effect of the adenohypophysis on structures of the breast and the development of dyshormonal processes in it].

An analysis of the morphofunctional relationships between hypophysis and female mammary gland is performed in 146 patients aging between 8 and 25 years. Both organs are studied using various histological, histochemical, morphometric and statistical methods. It is established that hypophysis influences actively on the mammogenesis not only in the incipient (12-16 years) and late (22-25 years) periods of sexual maturation but at other age periods as well. However the degree and character of this pituitary influences on the mammary gland are not the same this being shown by the results of a correlation analysis of relationship between pituitary and mammary gland indices. This seems to be due to both a direct and indirect influence of pituitary hormones on the mammogenesis as well as to the individual variability of mammary gland responses on the mammogenic effects. In rare cases mammary gland reacts on the ordinary hormonal stimulus by the development of pathological process.