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莱姆神经Borreliosis 表现为尿潴留和痉挛性截瘫。

Lyme neuroborreliosis presenting with urinary retention and spastic paraparesis.

机构信息

Department of Neurology, Zealand University Hospital, Roskilde, Denmark

Department of Neurology, Zealand University Hospital, Roskilde, Denmark.

出版信息

Pract Neurol. 2023 Nov 23;23(6):504-506. doi: 10.1136/pn-2023-003779.

DOI:10.1136/pn-2023-003779
PMID:37532431
Abstract

Progressive myelopathy, urinary retention and gait problems are rare presenting features of Lyme neuroborreliosis. A 30-year-old man had 11 months of urinary retention and 3 months of spastic paraparesis. MR scans of the brain and the spinal cord showed leptomeningeal thickening with contrast enhancement. Cerebrospinal fluid showed mononuclear pleocytosis, decreased glucose, increased protein and chemokine ligand 13, with intrathecal -specific IgM and IgG antibodies. He received 14 days of intravenous ceftriaxone followed by 14 days of oral doxycycline. Despite improvement at 6 months, he still had severe gait problems. Urinary retention in otherwise healthy people needs investigation, and Lyme neuroborreliosis is a rare cause.

摘要

进行性脊髓病、尿潴留和步态问题是莱姆神经Borreliosis 的罕见表现特征。一名 30 岁男子出现 11 个月尿潴留和 3 个月痉挛性截瘫。大脑和脊髓的磁共振成像显示脑膜增厚伴对比增强。脑脊液显示单核细胞增多症、葡萄糖减少、蛋白和趋化因子配体 13 增加,伴有鞘内特异性 IgM 和 IgG 抗体。他接受了 14 天的静脉注射头孢曲松,随后又接受了 14 天的口服强力霉素。尽管在 6 个月时有所改善,但他仍有严重的步态问题。在其他方面健康的人中,尿潴留需要进行调查,而莱姆神经Borreliosis 是一种罕见的病因。

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