Purohit Rajveer S, Blaivas Jerry G, Weinberger James M, Deibert Christopher M
Weill Medical College of Cornell University, New York, New York.
SUNY Downstate College of Medicine, Brooklyn, New York.
Urol Pract. 2014 May;1(1):35-39. doi: 10.1016/j.urpr.2014.02.001. Epub 2014 Mar 4.
Currently there is no widely accepted staging system for anterior urethral strictures. We developed and evaluated the reliability of an easy to use classification system for anterior urethral strictures in men.
We devised a staging system based on cystoscopic findings of no stricture (stage 0), wide caliber stricture (stage 1), stricture requires gentle dilation with a 16Fr flexible cystoscope (stage 2), stricture cannot be dilated (stage 3) and no visible lumen (stage 4). Content validity was established by a panel of 5 urologists. On 2 separate occasions 3 urologists independently viewed videos obtained during cystoscopy and staged the tightest visible stricture. If multiple strictures were present, the stricture with the smallest visible lumen was used for the purpose of this study. All men who had undergone cystoscopy at our institution between 2011 and 2012 were included in the study. Exclusion criteria were poor video quality and not visualizing the entire urethra during cystoscopy.
A total of 101 videos of consecutive cystoscopies were reviewed. Intra-observer agreement was 76% to 94% (Cohen κ 0.65-0.90) and interobserver agreement was 73% to 82% (Cohen κ 0.51-1.00, 0.69 overall, p <0.001). The intra-observer and interobserver agreement increased for each stage, with 3 and 4 almost unanimously identified by all 3 observers (Cohen κ 0.93 and 1.00, p <0.001).
This new staging system is simple and easy to use, and has excellent intra-observer and good interobserver reliability. The staging system provides a simple lexicon for describing the appearance of anterior urethral strictures.
目前尚无广泛接受的前尿道狭窄分期系统。我们开发并评估了一种易于使用的男性前尿道狭窄分类系统的可靠性。
我们基于膀胱镜检查结果设计了一种分期系统,无狭窄(0期)、宽口径狭窄(1期)、狭窄需要用16Fr可弯曲膀胱镜轻柔扩张(2期)、狭窄无法扩张(3期)以及无可见管腔(4期)。由5名泌尿科医生组成的小组确定了内容效度。在两个不同的时间点,3名泌尿科医生独立查看膀胱镜检查期间获得的视频,并对最狭窄的可见狭窄进行分期。如果存在多个狭窄,则本研究使用可见管腔最小的狭窄。2011年至2012年期间在我们机构接受膀胱镜检查的所有男性均纳入本研究。排除标准为视频质量差和膀胱镜检查期间未观察到整个尿道。
共回顾了101份连续膀胱镜检查的视频。观察者内一致性为76%至94%(Cohen κ 0.65 - 0.90),观察者间一致性为73%至82%(Cohen κ 0.51 - 1.00,总体为0.69,p <0.001)。每个阶段的观察者内和观察者间一致性均有所提高,所有3名观察者几乎一致确定3期和4期(Cohen κ 0.93和1.00,p <0.001)。
这种新的分期系统简单易用,并具有出色的观察者内可靠性和良好的观察者间可靠性。该分期系统为描述前尿道狭窄的外观提供了一个简单的术语表。