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中国幼女外阴硬化性苔藓的反射共聚焦显微镜特征。

Reflectance confocal microscopy features of vulvar lichen sclerosus in Chinese juvenile girls.

机构信息

Department of Dermatology, Tianjin Children's Hospital/Tianjin University Children's Hospital, Tianjin, China.

Department of Otolaryngology, Tianjin Children's Hospital/Tianjin University Children's Hospital, Tianjin, China.

出版信息

J Dermatol. 2023 Nov;50(11):1497-1500. doi: 10.1111/1346-8138.16884. Epub 2023 Aug 2.

Abstract

Vulvar lichen sclerosus (VLS) is a chronic inflammatory dermatosis of unknown pathogenesis, characterized by porcelain-white atrophic plaques around the vulvar and anal areas in girls. With this communication, we performed the study on 16 female girls with clinically and histologically confirmed VLS, described the main identifying characteristics of the lesions in reflectance confocal microscopy (RCM) and elucidated the corresponding relationship between RCM findings and histology. We recommend RCM, a noninvasive technique, as a complementary diagnostic tool for VLS.

摘要

外阴硬化性苔藓(VLS)是一种病因不明的慢性炎症性皮肤病,其特征是在女孩的外阴和肛门周围出现瓷白色萎缩性斑块。通过本次交流,我们对 16 名经临床和组织学证实患有 VLS 的女性患者进行了研究,描述了反射共聚焦显微镜(RCM)下病变的主要特征,并阐明了 RCM 结果与组织学之间的对应关系。我们推荐 RCM 作为一种非侵入性技术,作为 VLS 的辅助诊断工具。

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