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合并正常双胎妊娠的完全性葡萄胎伴甲状腺功能亢进症并顺利分娩活婴:埃塞俄比亚沃莱塔索多的一例病例报告

Complete molar pregnancy with coexisting normal twin complicated by hyperthyroidism that resulted in normal alive delivery: A case report from Wolaita Sodo, Ethiopia.

作者信息

Yayna Amanuel Admasu, Ayza Adane, Dana Wokil Wolde, Yemaneh Amdetsiyon, Worana Bereket, Tesfaye Ashebir, Desalegn Abinet, Kassaye Getu, Adamu Ermias, Leka Yohannes Abraham, Tadesse Mulugeta, Gure Tadesse

机构信息

Department of Gynecology and Obstetrics, Wolaita Sodo University Comprehensive and Specialized Hospital, Sodo, Ethiopia.

Department of Pathology, Wolaita Sodo University Comprehensive and Specialized Hospital, Sodo, Ethiopia.

出版信息

SAGE Open Med Case Rep. 2023 Jul 31;11:2050313X231189404. doi: 10.1177/2050313X231189404. eCollection 2023.

Abstract

It is a rare condition in twin pregnancies for a fetus to coexist with a complete hydatidiform mole, present with complications, and result in a healthy neonate. Only a few cases have been reported upon review of the literature. Early diagnosis is essential because this type of pregnancy is associated with serious complications and management challenges. The complications associated with these pregnancies include antepartum hemorrhage, hyperthyroidism, preeclampsia, prematurity, fetal death, and gestational trophoblastic neoplasia. Here, we describe a case of dizygotic twin pregnancy in which a complete mole coexists with a normal fetus, complicated by hyperthyroidism, that resulted in the birth of a 1700-g female alive neonate who is euthyroid to a 25-year-old primigravida at a gestational age of 33 weeks by emergency cesarean section for an indication of a twin pregnancy molar coexisting with an alive fetus in labor. The mother had been on conservative management and treated as an inpatient for hyperthyroidism. In our country, there have been three case reports of partial moles with coexisting alive fetuses, but this is the first case report of a complete mole with a coexisting alive fetus.

摘要

在双胎妊娠中,胎儿与完全性葡萄胎共存、出现并发症并娩出健康新生儿是一种罕见的情况。查阅文献后仅报道了少数病例。早期诊断至关重要,因为这类妊娠会伴有严重并发症和管理挑战。与这些妊娠相关的并发症包括产前出血、甲状腺功能亢进、子痫前期、早产、胎儿死亡和妊娠滋养细胞肿瘤。在此,我们描述一例双卵双胎妊娠病例,其中一个完全性葡萄胎与一个正常胎儿共存,并伴有甲状腺功能亢进,在孕33周时,因双胎妊娠中一个葡萄胎与一个存活胎儿同时分娩的指征,通过急诊剖宫产为一名25岁初产妇娩出一名体重1700克的存活女婴,该女婴甲状腺功能正常。母亲一直在进行保守治疗,并作为甲状腺功能亢进的住院患者接受治疗。在我国,已有3例部分性葡萄胎与存活胎儿共存的病例报告,但这是首例完全性葡萄胎与存活胎儿共存的病例报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b926/10392214/7f236e00f9a0/10.1177_2050313X231189404-fig1.jpg

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