p16在肾源性腺瘤中的免疫组化表达
p16 Immunohistochemical Expression in Nephrogenic Adenoma.
作者信息
Alvarez Moreno Juan Carlos, Ghani Hafiz A, Ovechko Vasily, Clement Cecilia, Eyzaguirre Eduardo
机构信息
Pathology, University of Texas Medical Branch at Galveston, Galveston, USA.
出版信息
Cureus. 2023 Jul 2;15(7):e41285. doi: 10.7759/cureus.41285. eCollection 2023 Jul.
Nephrogenic adenoma (NA) is a rare metaplastic entity commonly associated with a prior urothelial injury. Most are seen in the urinary bladder and a minority involve the urethra. In this study, we evaluated the expression of p16 as a surrogate marker of this entity and correlated it with clinical pathological parameters. A total of 17 cases of NA were retrospectively studied to assess the immunohistochemical expression of p16 and its value for the diagnosis of this entity.
肾源性腺瘤（NA）是一种罕见的化生实体，通常与先前的尿路上皮损伤有关。大多数病例见于膀胱，少数累及尿道。在本研究中，我们评估了p16作为该实体替代标志物的表达情况，并将其与临床病理参数进行关联。总共对17例肾源性腺瘤进行了回顾性研究，以评估p16的免疫组化表达及其在该实体诊断中的价值。
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