Division of Neonatology, Department of Pediatrics, Heersink School of Medicine, University of Alabama at Birmingham, 1700 6th Avenue South Women & Infants Center Suite 9380, Birmingham, AL 35233, USA.
Division of Neonatology, Department of Pediatrics, Heersink School of Medicine, University of Alabama at Birmingham, 1700 6th Avenue South Women & Infants Center Suite 9380, Birmingham, AL 35233, USA.
Clin Perinatol. 2023 Sep;50(3):607-623. doi: 10.1016/j.clp.2023.04.005. Epub 2023 May 26.
Establishing full enteral nutrition in critically ill preterm infants with immature gastrointestinal function is challenging. In this article, we will summarize emerging clinical evidence from randomized clinical trials suggesting the feasibility and efficacy of feeding interventions targeting the early establishment of full enteral nutrition. We will also examine trial outcomes of higher volume feedings after the establishment of full enteral nutrition. Only data from randomized clinical trials will be discussed extensively. Future opportunities for clinical research will also be presented.
在胃肠道功能不成熟的危重症早产儿中建立完全肠内营养具有挑战性。本文总结了来自随机临床试验的新的临床证据,这些证据表明针对早期建立完全肠内营养的喂养干预措施具有可行性和有效性。我们还将检查完全肠内营养建立后增加喂养量的试验结果。本文将详细讨论仅来自随机临床试验的数据。还将介绍未来临床研究的机会。