Gastrointestinal Tumor Program, Division of Surgical Oncology, Department of Surgery, Cedars-Sinai Medical Center, 8700 Beverly Boulevard North Tower, Suite 8215, Los Angeles, CA 90048, USA.
Department of Surgery, Cedars-Sinai Medical Center, 8700 Beverly Boulevard North Tower, Suite 8215, Los Angeles, CA 90048, USA.
Adv Surg. 2023 Sep;57(1):47-58. doi: 10.1016/j.yasu.2023.06.001.
Well-differentiated nonfunctional pancreatic neuroendocrine tumors are often indolent neoplasms without lymph node (LN) metastasis at diagnosis. Patients with PNETs that are functional or >2 cm should have surgical resection as per the standard of care. However, in appropriately selected patients with NF PNETs <2 cm who are at low risk of LN metastasis, the extent of surgery and lymphadenectomy could be limited.
分化良好的无功能性胰腺神经内分泌肿瘤通常为惰性肿瘤，在诊断时无淋巴结（LN）转移。功能性或直径>2cm 的 PNET 患者应根据标准护理进行手术切除。然而，对于适当选择的 LN 转移风险低的<2cm 的 NF PNET 患者，手术和淋巴结清扫的范围可以有限。
