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原发性肾上腺假性囊肿血管起源的免疫组织化学证据

Immunohistochemical evidence for the vascular origin of primary adrenal pseudocysts.

作者信息

Groben P A, Roberson J B, Anger S R, Askin F B, Price W G, Siegal G P

出版信息

Arch Pathol Lab Med. 1986 Feb;110(2):121-3.

PMID:3753843
Abstract

Pseudocysts are the most common nonfunctioning cystic adrenal lesions associated with symptoms. We have studied tissue from two patients with large adrenal pseudocysts in whom no antecedent cause could be documented. Immunohistochemical examination of these formaldehyde-fixed paraffin-embedded tissues with antibodies directed against the major proteins of the basement membrane (laminin and type IV collagen) revealed intense linear staining surrounding the cystic spaces and at the compressed adrenal cortical/pseudocyst interface. These findings lead us to conclude that these lesions are vascular in nature and, therefore, closely related to the previously recognized adrenal cysts of endothelial origin.

摘要

假性囊肿是最常见的与症状相关的无功能肾上腺囊性病变。我们研究了两名患有巨大肾上腺假性囊肿且无前驱病因记录的患者的组织。用针对基底膜主要蛋白(层粘连蛋白和IV型胶原)的抗体对这些甲醛固定石蜡包埋组织进行免疫组化检查,发现囊腔周围以及受压的肾上腺皮质/假性囊肿界面有强烈的线性染色。这些发现使我们得出结论,这些病变本质上是血管性的,因此与先前公认的内皮起源的肾上腺囊肿密切相关。

相似文献

1
Immunohistochemical evidence for the vascular origin of primary adrenal pseudocysts.原发性肾上腺假性囊肿血管起源的免疫组织化学证据
Arch Pathol Lab Med. 1986 Feb;110(2):121-3.
2
Vascular adrenal cysts: a clinicopathologic and immunohistochemical study of six cases and a review of the literature.肾上腺血管性囊肿:6例临床病理及免疫组化研究并文献复习
Mod Pathol. 1997 Jun;10(6):530-6.
3
Morphology and pathogenesis of adrenal cysts.肾上腺囊肿的形态学与发病机制。
Am J Pathol. 1979 May;95(2):423-32.
4
Vascular adrenal cysts. A clinicopathologic and immunohistochemical study of endothelial and hemorrhagic (pseudocystic) variants.肾上腺血管性囊肿。内皮型和出血性(假性囊肿性)变异型的临床病理及免疫组织化学研究
Am J Surg Pathol. 1989 Sep;13(9):740-7.
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[Giant pseudocysts of the adrenal gland. Clinico-pathologic study of 2 cases].[肾上腺巨大假性囊肿。2例临床病理研究]
Arch Esp Urol. 1991 Sep;44(7):821-5.
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[Vascular cysts of the adrenals. Association with aneurysm of the abdominal aorta].[肾上腺血管囊肿。与腹主动脉瘤的关联]
Ann Ital Chir. 1999 May-Jun;70(3):445-50.
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Adrenal pseudocyst: a clinical and pathologic study of eight cases.肾上腺假性囊肿:8例临床与病理研究
Hum Pathol. 1989 Jul;20(7):660-5. doi: 10.1016/0046-8177(89)90153-6.
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Adrenal cystic lesions: a clinicopathological analysis of 25 cases with proposed histogenesis and review of the literature.肾上腺囊性病变:25例临床病理分析及组织发生学探讨并文献复习
Endocr Pathol. 2008 Winter;19(4):274-81. doi: 10.1007/s12022-008-9046-y.
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Cysts of the adrenal gland: revision of a 15-year experience.肾上腺囊肿:15年经验回顾
Anticancer Res. 2001 Mar-Apr;21(2B):1401-6.
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[Endothelial cyst in the adrenal gland].[肾上腺内皮囊肿]
Ugeskr Laeger. 1993 Aug 23;155(34):2629-30.

引用本文的文献

1
Giant hemorrhagic adrenal pseudocyst in a primiparous pregnancy: report of a case.初产妇妊娠中巨大出血性肾上腺假性囊肿 1 例报告
Surg Today. 2011 Jan;41(1):153-8. doi: 10.1007/s00595-009-4207-2. Epub 2010 Dec 30.
2
Laparoscopic resection of an adrenal pseudocyst mimicking a retroperitoneal mucinous cystic neoplasm.腹腔镜下切除一例酷似腹膜后黏液性囊性肿瘤的肾上腺假性囊肿。
World J Gastroenterol. 2009 Jun 21;15(23):2923-6. doi: 10.3748/wjg.15.2923.
3
Adrenal cystic lesions: a clinicopathological analysis of 25 cases with proposed histogenesis and review of the literature.
肾上腺囊性病变:25例临床病理分析及组织发生学探讨并文献复习
Endocr Pathol. 2008 Winter;19(4):274-81. doi: 10.1007/s12022-008-9046-y.
4
[An adrenal pseudocyst as the cause of chronic back pain].[肾上腺假性囊肿作为慢性背痛的病因]
Orthopade. 2005 Dec;34(12):1263-6. doi: 10.1007/s00132-005-0873-y.
5
Adrenal Pseudocysts: Evidence of Their Posthemorrhagic Nature.
Endocr Pathol. 1998 Winter;9(1):353-361. doi: 10.1007/BF02739696.