实现 PET 对 α-突触核蛋白成像。

Toward imaging of alpha-synuclein with PET.

机构信息

Department of Radiology, Division of Neuroradiology, Mayo Clinic, Rochester, MN, USA.

出版信息

Cell. 2023 Aug 3;186(16):3327-3329. doi: 10.1016/j.cell.2023.06.018.

DOI:10.1016/j.cell.2023.06.018

Abstract

Development of radiopharmaceuticals for in vivo positron emission tomography imaging of alpha-synuclein aggregates has the potential to revolutionize Lewy body disease diagnosis and treatment. Reporting in this issue of Cell, Xiang et al. developed a high-affinity positron emission tomography tracer for alpha-synuclein.

摘要

研发用于活体正电子发射断层扫描成像α-突触核蛋白聚集体的放射性药物有可能彻底改变路易体病的诊断和治疗。在本期《细胞》杂志中，项等人开发了一种高亲和力的α-突触核蛋白正电子发射断层扫描示踪剂。