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ARHGAP6 transcript levels are associated with molecular risk and impact survival outcomes in acute myeloid leukemia.

作者信息

Lipreri da Silva Jean Carlos, Coelho-Silva Juan Luiz, Vicari Hugo Passos, Lima Keli, Rego Eduardo Magalhães, Traina Fabiola, Machado-Neto João Agostinho

机构信息

Institute of Biomedical Sciences, University de São Paulo (USP), São Paulo, SP, Brazil.

Hematology and Clinical Oncology, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (FMUSP), Ribeirão Preto, SP, Brazil.

出版信息

Hematol Transfus Cell Ther. 2024 Jan-Mar;46(1):101-105. doi: 10.1016/j.htct.2023.06.004. Epub 2023 Jul 31.

DOI:10.1016/j.htct.2023.06.004
PMID:37541806
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10935455/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/818b/10935455/e7c356b395d4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/818b/10935455/e7c356b395d4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/818b/10935455/e7c356b395d4/gr1.jpg

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本文引用的文献

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ARHGAP6 inhibits bladder cancer cell viability, migration, and invasion via β-catenin signaling and enhances mitomycin C sensitivity.ARHGAP6 通过 β-catenin 信号通路抑制膀胱癌细胞活力、迁移和侵袭，并增强丝裂霉素 C 的敏感性。
Hum Cell. 2023 Mar;36(2):786-797. doi: 10.1007/s13577-023-00860-3. Epub 2023 Jan 30.
2
International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data.国际髓系肿瘤和急性白血病分类：整合形态学、临床和基因组数据。
Blood. 2022 Sep 15;140(11):1200-1228. doi: 10.1182/blood.2022015850.
3
Comprehensive analysis of cytoskeleton regulatory genes identifies ezrin as a prognostic marker and molecular target in acute myeloid leukemia.
细胞骨架调控基因的综合分析确定埃兹蛋白为急性髓系白血病的预后标志物和分子靶点。
Cell Oncol (Dordr). 2021 Oct;44(5):1105-1117. doi: 10.1007/s13402-021-00621-0. Epub 2021 Jul 1.
4
ARHGAP6 Promotes Apoptosis and Inhibits Glycolysis in Lung Adenocarcinoma Through STAT3 Signaling Pathway.ARHGAP6通过STAT3信号通路促进肺腺癌细胞凋亡并抑制糖酵解
Cancer Manag Res. 2020 Oct 6;12:9665-9678. doi: 10.2147/CMAR.S257759. eCollection 2020.
5
Combining gene mutation with gene expression analysis improves outcome prediction in acute promyelocytic leukemia.将基因突变与基因表达分析相结合可提高急性早幼粒细胞白血病的预后预测。
Blood. 2019 Sep 19;134(12):951-959. doi: 10.1182/blood.2019000239. Epub 2019 Jul 10.
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ARHGAP6 regulates the proliferation, migration and invasion of lung cancer cells.ARHGAP6 调控肺癌细胞的增殖、迁移和侵袭。
Oncol Rep. 2019 Apr;41(4):2281-2888. doi: 10.3892/or.2019.7031. Epub 2019 Feb 25.
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Inhibitory effects of Arhgap6 on cervical carcinoma cells.Arhgap6对宫颈癌细胞的抑制作用。
Tumour Biol. 2016 Feb;37(2):1411-25. doi: 10.1007/s13277-015-4502-z. Epub 2015 Dec 1.
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Acute Myeloid Leukemia.急性髓系白血病
N Engl J Med. 2015 Sep 17;373(12):1136-52. doi: 10.1056/NEJMra1406184.
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