National Center of Ultrasound in Gastroenterology, Haukeland University Hospital, Bergen, Norway.
Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, AB, Canada.
BMC Gastroenterol. 2023 Aug 5;23(1):265. doi: 10.1186/s12876-023-02882-5.
We read with interest the study by Freitas et al. comparing contrast-enhanced ultrasound (CEUS) and parameters from a time-intensity curve (TIC) with the SUS-CD score and IBUS-SAS score in patients with Crohn's disease (CD) undergoing gastrointestinal ultrasound (GIUS) and ileocolonoscopy. The aim was to compare the accuracy of CEUS and aforementioned scores in predicting terminal ileal inflammatory activity in patients with CD. In this retrospective study of 50 patients, inflammatory activity was defined as a segmental score of SES-CD ≥ 7 in the terminal ileum. The study found 30 patients with active endoscopic disease demonstrating no significant difference between the "inactive" and "active" SUS CD and IBUS-SAS scores. However, the CEUS peak enhancement derived from the TIC was shown to be significantly different. The authors conclude CEUS was superior for detecting inflammation in the terminal ileum, as opposed to ultrasound scores relying on bowel wall thickness and color Doppler.
我们饶有兴趣地阅读了 Freitas 等人的研究，该研究比较了对比增强超声（CEUS）和时间强度曲线（TIC）参数与克罗恩病（CD）患者胃肠道超声（GIUS）和回结肠镜检查的 SUS-CD 评分和 IBUS-SAS 评分，旨在比较 CEUS 和上述评分在预测 CD 患者末端回肠炎症活动中的准确性。在这项对 50 名患者的回顾性研究中，炎症活动定义为末端回肠 SES-CD≥7 的节段评分。研究发现 30 名内镜下有活动性疾病的患者，其“不活动”和“活动”的 SUS-CD 和 IBUS-SAS 评分之间无显著差异。然而，TIC 得出的 CEUS 峰值增强则显示出显著差异。作者得出结论，CEUS 优于检测末端回肠炎症，而不是依赖肠壁厚度和彩色多普勒的超声评分。
