• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Dr. Johnstone et al. Reply to Dr. Elmrayed.约翰斯通博士等回复埃尔迈雷德博士。
J Am Acad Child Adolesc Psychiatry. 2023 Nov;62(11):1171-1175. doi: 10.1016/j.jaac.2023.07.994. Epub 2023 Aug 3.
2
Dr. Johnstone et al. Reply to Dr. Hamilton.约翰斯通博士等回复汉密尔顿博士。
J Am Acad Child Adolesc Psychiatry. 2023 Nov;62(11):1168-1170. doi: 10.1016/j.jaac.2023.07.992. Epub 2023 Aug 3.
3
Editorial: Accumulating Evidence for the Benefit of Micronutrients for Children With Attention-Deficit/Hyperactivity Disorder.社论：越来越多的证据表明微量营养素对注意力缺陷/多动障碍儿童有益。
J Am Acad Child Adolesc Psychiatry. 2022 May;61(5):599-600. doi: 10.1016/j.jaac.2021.08.008. Epub 2021 Aug 17.
4
Dosages of Nutrient Supplements and Potential Long-Term Toxicity in Attention-Deficit/Hyperactivity Disorder Micronutrient Study.注意缺陷多动障碍微量营养素研究中的营养素补充剂剂量和潜在长期毒性。
J Am Acad Child Adolesc Psychiatry. 2023 Nov;62(11):1170-1171. doi: 10.1016/j.jaac.2023.01.027. Epub 2023 Aug 3.
5
Clinically Significant Symptom Reduction in Children with Attention-Deficit/Hyperactivity Disorder Treated with Micronutrients: An Open-Label Reversal Design Study.使用微量营养素治疗的注意力缺陷/多动障碍儿童临床显著症状减轻：一项开放标签反向设计研究。
J Child Adolesc Psychopharmacol. 2015 Dec;25(10):783-98. doi: 10.1089/cap.2015.0105.
6
Dr. Sucksdorff et al. Reply.萨克斯多夫博士等人的回复。
J Am Acad Child Adolesc Psychiatry. 2021 Oct;60(10):1167-1168. doi: 10.1016/j.jaac.2021.04.009. Epub 2021 May 5.
7
Can we predict treatment response in children with ADHD to a vitamin-mineral supplement? An investigation into pre-treatment nutrient serum levels, MTHFR status, clinical correlates and demographic variables.我们能否预测 ADHD 儿童对维生素-矿物质补充剂的治疗反应？对治疗前营养素血清水平、MTHFR 状态、临床相关性和人口统计学变量的调查。
Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 8;89:181-192. doi: 10.1016/j.pnpbp.2018.09.007. Epub 2018 Sep 12.
8
Dr. Øvergaard et al. Reply.奥弗高教授等人的答复。
J Am Acad Child Adolesc Psychiatry. 2018 Sep;57(9):701-702. doi: 10.1016/j.jaac.2018.05.021.
9
Moderators of treatment response in adults with ADHD treated with a vitamin-mineral supplement.维生素-矿物质补充剂治疗成人 ADHD 治疗反应的调节剂。
Prog Neuropsychopharmacol Biol Psychiatry. 2014 Apr 3;50:163-71. doi: 10.1016/j.pnpbp.2013.12.014. Epub 2013 Dec 26.
10
Vitamin-mineral treatment improves aggression and emotional regulation in children with ADHD: a fully blinded, randomized, placebo-controlled trial.维生素-矿物质治疗可改善 ADHD 儿童的攻击行为和情绪调节：一项完全盲法、随机、安慰剂对照试验。
J Child Psychol Psychiatry. 2018 Mar;59(3):232-246. doi: 10.1111/jcpp.12817. Epub 2017 Oct 2.

引用本文的文献

1
Gut microbiome changes with micronutrient supplementation in children with attention-deficit/hyperactivity disorder: the MADDY study.注意缺陷多动障碍儿童补充微量营养素后肠道微生物群的变化：MADDY研究
Gut Microbes. 2025 Dec;17(1):2463570. doi: 10.1080/19490976.2025.2463570. Epub 2025 Feb 18.
2
Broad spectrum micronutrients: a potential key player to address emotional dysregulation.广谱微量营养素：解决情绪失调问题的潜在关键因素。
Front Child Adolesc Psychiatry. 2023 Dec 15;2:1295635. doi: 10.3389/frcha.2023.1295635. eCollection 2023.
3
Annual Research Review: Micronutrients and their role in the treatment of paediatric mental illness.年度研究综述：微量营养素及其在儿童精神疾病治疗中的作用。
J Child Psychol Psychiatry. 2025 Apr;66(4):477-497. doi: 10.1111/jcpp.14091. Epub 2024 Dec 20.

本文引用的文献

1
Dosages of Nutrient Supplements and Potential Long-Term Toxicity in Attention-Deficit/Hyperactivity Disorder Micronutrient Study.注意缺陷多动障碍微量营养素研究中的营养素补充剂剂量和潜在长期毒性。
J Am Acad Child Adolesc Psychiatry. 2023 Nov;62(11):1170-1171. doi: 10.1016/j.jaac.2023.01.027. Epub 2023 Aug 3.
2
Correction.修正。
J Am Acad Child Adolesc Psychiatry. 2022 Aug;61(8):1066. doi: 10.1016/j.jaac.2022.04.021. Epub 2022 May 6.
3
Micronutrients for Attention-Deficit/Hyperactivity Disorder in Youths: A Placebo-Controlled Randomized Clinical Trial.青少年注意缺陷多动障碍的微量营养素：一项安慰剂对照随机临床试验。
J Am Acad Child Adolesc Psychiatry. 2022 May;61(5):647-661. doi: 10.1016/j.jaac.2021.07.005. Epub 2021 Jul 22.
4
The Role of Lead, Manganese, and Zinc in Autism Spectrum Disorders (ASDs) and Attention-Deficient Hyperactivity Disorder (ADHD): a Case-Control Study on Syrian Children Affected by the Syrian Crisis.铅、锰和锌在自闭症谱系障碍（ASD）和注意缺陷多动障碍（ADHD）中的作用：叙利亚危机影响下的叙利亚儿童病例对照研究。
Biol Trace Elem Res. 2020 Sep;197(1):107-114. doi: 10.1007/s12011-020-02146-3. Epub 2020 Apr 28.
5
Rationale and design of an international randomized placebo-controlled trial of a 36-ingredient micronutrient supplement for children with ADHD and irritable mood: The Micronutrients for ADHD in Youth (MADDY) study.一项针对患有注意力缺陷多动障碍（ADHD）且情绪烦躁的儿童的36种成分微量营养素补充剂的国际随机安慰剂对照试验的原理与设计：青少年ADHD微量营养素（MADDY）研究
Contemp Clin Trials Commun. 2019 Oct 26;16:100478. doi: 10.1016/j.conctc.2019.100478. eCollection 2019 Dec.
6
An Observational Preliminary Study on the Safety of Long-Term Consumption of Micronutrients for the Treatment of Psychiatric Symptoms.长期服用微量营养素治疗精神症状安全性的观察性初步研究
J Altern Complement Med. 2019 Jun;25(6):613-622. doi: 10.1089/acm.2018.0352. Epub 2019 May 13.
7
Significantly lower serum and hair magnesium levels in children with attention deficit hyperactivity disorder than controls: A systematic review and meta-analysis.患有注意缺陷多动障碍的儿童的血清和头发镁水平明显低于对照组：系统评价和荟萃分析。
Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 2;90:134-141. doi: 10.1016/j.pnpbp.2018.11.012. Epub 2018 Nov 26.
8
Association between peripheral manganese levels and attention-deficit/hyperactivity disorder: a preliminary meta-analysis.外周锰水平与注意力缺陷多动障碍之间的关联：一项初步的荟萃分析。
Neuropsychiatr Dis Treat. 2018 Jul 18;14:1831-1842. doi: 10.2147/NDT.S165378. eCollection 2018.
9
Manganese Toxicity Upon Overexposure: a Decade in Review.锰暴露过度毒性：十年综述。
Curr Environ Health Rep. 2015 Sep;2(3):315-28. doi: 10.1007/s40572-015-0056-x.
10
Systematic review of safety and tolerability of a complex micronutrient formula used in mental health.用于心理健康的复合微量营养素配方的安全性和耐受性的系统评价。
BMC Psychiatry. 2011 Apr 18;11:62. doi: 10.1186/1471-244X-11-62.

约翰斯通博士等回复埃尔迈雷德博士。

Dr. Johnstone et al. Reply to Dr. Elmrayed.

机构信息

Oregon Health & Science University, Portland, Oregon; National University of Natural Medicine, Helfgott Research Institute, Portland, Oregon.

The Ohio State University, Columbus, Ohio.

出版信息

J Am Acad Child Adolesc Psychiatry. 2023 Nov;62(11):1171-1175. doi: 10.1016/j.jaac.2023.07.994. Epub 2023 Aug 3.

DOI:10.1016/j.jaac.2023.07.994
PMID:37543077
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11342338/
Abstract

We thank Dr. Elmrayed and colleagues for highlighting clinical cautions in using broad-spectrum micronutrients to treat attention-deficit/hyperactivity disorder (ADHD) in children, in particular manganese (Mn) levels. We appreciate the opportunity to provide additional information and rationale for the vitamin and mineral doses contained in the studied formula.

摘要

我们感谢 Elmrayed 博士及其同事强调了在儿童中使用广谱微量营养素治疗注意缺陷多动障碍（ADHD）时的临床注意事项，特别是锰（Mn）水平。我们很荣幸有机会为研究配方中包含的维生素和矿物质剂量提供更多信息和基本原理。