University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia.
University Clinical Center of Vojvodina, Clinic of Obstetrics and Gynecology, Novi Sad, Serbia.
Medicine (Baltimore). 2023 Aug 4;102(31):e34451. doi: 10.1097/MD.0000000000034451.
Necrotizing fasciitis is rapidly progressive infection with high mortality rate. This study aimed to summarize the clinical and pathological presentation of this case.
A 46-year-old woman patient presented to our emergency department of an obstetric and gynecology clinic on the 8th day after total abdominal hysterectomy. The abdominal wall showed pronounced signs of inflammation. Abundant purulent content was oozing from the abdominal wound.
The patient underwent surgery. Areas of necrosis were observed on the skin around the wound, the subcutaneous fatty tissue was necrotic around the incision site, and the fascia was completely dehisced.
Wound debridement and flap cutting of the anterior abdominal wall were performed. Metronidazole, ceftriaxone, and vancomycin were administered intravenously. A plastic surgeon suggested daily debridement and toileting of the wound in the operating room. Swabs of the abdominal cavity, abscess cavity, and abdominal wound were obtained, and Enterococcus faecalis was isolated. After the negativism of microbiological swabs, excochleation of granulation tissue was performed by a plastic surgeon.
Nineteen days after the relaparotomy, the patient was discharged in good general condition with advice for further monitoring and therapy.
Successful treatment of necrotizing fasciitis can be achieved through an initial diagnosis, adequate debridement, empirical broad-spectrum antibiotic coverage, and multidisciplinary treatment.
坏死性筋膜炎是一种进展迅速、死亡率高的感染。本研究旨在总结该病例的临床和病理表现。
一名 46 岁女性患者在全子宫切除术后第 8 天到妇产科诊所的急诊就诊。腹壁明显有炎症迹象。腹部伤口渗出大量脓性内容物。
患者接受了手术。观察到伤口周围的皮肤有坏死区域,切口部位的皮下脂肪组织坏死,筋膜完全裂开。
进行了伤口清创和前腹壁皮瓣切割。静脉注射甲硝唑、头孢曲松和万古霉素。整形外科医生建议每天在手术室对伤口进行清创和换药。腹腔、脓肿腔和腹部伤口的拭子均获得,并分离出粪肠球菌。在微生物拭子转为阴性后,整形外科医生对肉芽组织进行了 excochleation。
再次剖腹手术后 19 天,患者一般情况良好出院,并建议进一步监测和治疗。
通过早期诊断、充分清创、经验性广谱抗生素覆盖和多学科治疗,可以成功治疗坏死性筋膜炎。