Elling D, Bader K
Arch Geschwulstforsch. 1986;56(1):23-33.
A continuous monitoring by chromatographic determination of 10 free serum amino acids was carried out in 21 breast cancer patients. The results show, that the pretherapeutic levels of asparagine, glutamine, alanine, isoleucine, leucine, tyrosine and phenylalanine are significantly elevated if the disease progressed within the next two years. Asparagine, glutamine, glycine, alanine, tyrosine and phenylalanine are significantly elevated if no progression could be observed. In patients without progression the level of free serum amino acid went back to normal during one year. The determination of free serum amino acid is qualified for monitoring the treatment results in breast cancer patients.