Department of Orthopedics, Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing Province, Zhejiang, China; Department of Orthopedics, Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
Department of Radiology, Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
World Neurosurg. 2023 Dec;180:e56-e68. doi: 10.1016/j.wneu.2023.07.146. Epub 2023 Aug 4.
To assess the consistency and accuracy of various measurements of the Hounsfield unit (HU) in lumbar vertebrae.
The study reviewed lumbar spine computed tomography images of 60 postmenopausal women aged >50 years. A total of 240 vertebrae were measured and analyzed for the variations of HU values in different sections and regions. Investigated the relationship between HU values of the lumbar spine under different measurements and dual-energy X-ray absorptiometry results and the ability to identify patients with osteoporosis.
HU values measured in midsagittal (r = 0.763), midcoronal (r = 0.768), and midaxial (r = 0.786) sections exhibited a strong positive correlation with dual-energy X-ray absorptiometry T-scores. HU values measured in midsagittal and midaxial sections of the vertebral body were in good agreement (P > 0.1), but decreased in the midcoronal (P < 0.001). HU values in the middle of the vertebral body were significantly higher than in the near end plate (P < 0.001). HU values varied between L1 and L4 vertebrae, but all had a good ability to identify osteoporosis and did not differ significantly in screening ability (P > 0.05).
An averaged HU value in axial multilevel is a comprehensive assessment of vertebral bone density. Using the HU value of the lumbar spine can help identify patients with osteoporosis, and the screening ability does not differ significantly across vertebral segments.
评估腰椎 Hounsfield 单位（HU）的各种测量值的一致性和准确性。
本研究回顾了 60 名年龄>50 岁的绝经后女性的腰椎 CT 图像。共测量和分析了 240 个椎体，以研究不同节段和区域 HU 值的变化。探讨了不同测量方法下腰椎 HU 值与双能 X 线吸收仪结果的关系以及识别骨质疏松症患者的能力。
中矢状位（r=0.763）、中冠状位（r=0.768）和中轴位（r=0.786）测量的 HU 值与双能 X 线吸收仪 T 值呈强正相关。椎体中矢状位和中轴位测量的 HU 值一致性较好（P>0.1），但中冠状位（P<0.001）降低。椎体中部的 HU 值明显高于近终板（P<0.001）。L1 至 L4 椎体之间的 HU 值存在差异，但均具有良好的骨质疏松症识别能力，筛查能力无显著差异（P>0.05）。
轴向多层面的平均 HU 值是对椎体骨密度的综合评估。使用腰椎 HU 值有助于识别骨质疏松症患者，且各椎体节段的筛查能力无显著差异。
