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单一三级医疗中心脊髓蛛网膜囊肿手术经验分析及文献综述

Spinal Arachnoid Cyst Analysis of Surgical Experience in a Single Tertiary Care Centre and Review of Literature.

作者信息

Joseph Jeena, Raju Krishna Prabhu, Jonathan Edmond, Makkina Charan

机构信息

Department of Neurological Sciences, Christian Medical College, Vellore, India.

Department of Neurological Sciences, Christian Medical College, Vellore, India.

出版信息

World Neurosurg. 2023 Oct;178:e731-e740. doi: 10.1016/j.wneu.2023.07.151. Epub 2023 Aug 6.

Abstract

OBJECTIVE

To study patients with spinal arachnoid cysts, who underwent cyst excision with dural defect repair or marsupialization, and their outcomes.

METHODS

The retrospective analysis involved reviewing the records of 38 patients who underwent surgical treatment for spinal arachnoid cysts in the Department of Neurosurgery at Christian Medical College, Vellore, between August 2004 and December 2022. The study examined the demographics, clinical presentation, imaging, surgical intervention, and outcomes of these patients.

RESULTS

The majority of patients in the study were male (29/38, with 76.3%) and the thoracic region was the most common location for the cyst (17, with 44.7%). Weakness was the primary complaint and 94.7% of patients had myelopathy. The bladder was affected in 13 patients (34.2%). Of the 38 patients, 26 (71%) had cysts in extradural locations, while the rest were intradural. In total, 45.5% of intradural cysts were located in the ventral region. Seventeen (65.4%) had dural defects along the root sleeve and 29 (76.3%) underwent complete excision. All extradural cysts underwent complete excision and repair of the dural defect. Thirty patients (78.9%) experienced improved outcomes with reduced spasticity and improved weakness. One patient developed new-onset weakness postoperatively due to epidural hematoma. The mean follow-up period was 41 months and one patient experienced a recurrence.

CONCLUSIONS

Spinal arachnoid cyst is a rare benign spinal condition that is typically treated with surgery in symptomatic patients. Surgical intervention may involve either the excision of the cyst or marsupialization.

摘要

目的

研究接受囊肿切除并伴有硬脑膜缺损修复或囊肿开窗术的脊髓蛛网膜囊肿患者及其治疗结果。

方法

回顾性分析2004年8月至2022年12月期间在韦洛尔基督教医学院神经外科接受脊髓蛛网膜囊肿手术治疗的38例患者的记录。该研究调查了这些患者的人口统计学特征、临床表现、影像学检查、手术干预措施及治疗结果。

结果

该研究中的大多数患者为男性(29/38,占76.3%),囊肿最常见于胸段(17例,占44.7%)。无力是主要症状,94.7%的患者患有脊髓病。13例患者(34.2%)膀胱功能受到影响。38例患者中,26例(71%)的囊肿位于硬膜外,其余位于硬膜内。硬膜内囊肿中有45.5%位于腹侧区域。17例(65.4%)沿神经根袖有硬脑膜缺损,29例(76.3%)接受了完整切除。所有硬膜外囊肿均接受了完整切除及硬脑膜缺损修复。30例患者(78.9%)的病情得到改善,痉挛减轻,无力症状改善。1例患者术后因硬膜外血肿出现新发无力症状。平均随访期为41个月,1例患者出现复发。

结论

脊髓蛛网膜囊肿是一种罕见的良性脊髓疾病,有症状的患者通常采用手术治疗。手术干预可能包括囊肿切除或囊肿开窗术。

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