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[δ-睡眠肽对心脏节律副交感神经调节的作用]

[Effect of the delta-sleep peptide on parasympathetic regulation of the cardiac rhythm].

作者信息

Zviagintseva M A, Kosharskaia I L, Ul'ianinskiĭ L S

出版信息

Biull Eksp Biol Med. 1986 Apr;101(4):390-1.

PMID:3754472
Abstract

Effect of delta-sleep peptide (60 nM/kg) on the parasympathetic regulation of cardiac activity has been studied in the experiments on rabbits. It has been established that intravenous administration of this peptide to voluntary-behaving animals results in heart rate reduction by an average of 16%, that can be eliminated by atropine. Delta-sleep peptide has been demonstrated to intensify negative chronotropic effect in the case of directly irritated wandering nerve. The data obtained explain a protective effect of delta-sleep peptide on the heart under emotional stress.

摘要

在兔实验中研究了δ-睡眠肽(60 nM/kg)对心脏活动副交感神经调节的影响。已确定,对自主活动的动物静脉注射该肽会导致心率平均降低16%,阿托品可消除这种降低。已证明,在直接刺激迷走神经的情况下,δ-睡眠肽会增强负性变时效应。所获得的数据解释了δ-睡眠肽在情绪应激下对心脏的保护作用。

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