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[Lenke 5型青少年特发性脊柱侧凸手术后近端交界性后凸相关因素分析]

[Analysis of factors associated with proximal junctional kyphosis after surgery for Lenke type 5 adolescent idiopathic scoliosis].

作者信息

Li Q D, He B R, Hui H, Gao L, Yang J S, Liu T J, Zheng B L, Chang Z, Huang Y F, Zhao Z G, Du J P, Hao D J

机构信息

Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2023 Aug 8;103(29):2239-2245. doi: 10.3760/cma.j.cn112137-20221209-02607.

Abstract

To investigate the risk factors associated with the development of proximal junctional kyphosis (PJK) after posterior spinal fusion for in children with Lenke type 5 adolescent idiopathic scoliosis (AIS). It was a retrospective case-control study that included medical records of 98 children with Lenke type 5 AIS who underwent posterior orthopedic surgery under general anesthesia at the Honghui Hospital Affiliated to Xi'an Jiaotong University from January 2013 to December 2018. There were 23 males and 75 females with a mean age of (14.5±2.2) years (10-18 years). Patients were divided into PJK and non-PJK groups according to whether the posterior junctional angle (PJA) was greater than 10° and increased for more than 10° from the preoperative period at the the last follow-up. Univariate analysis was used to analyze the correlation of general data of the children with occurrence of PJK after the operation. Multivariate logistic regression analysis was used to analyze the risk factors of postoperative PJK. There were 35 cases in the PJK group and 63 cases in the non-PJK group. The PJK and non-PJK groups were followed up for (35.6±7.3) months and (36.4±7.5) months, respectively, and the difference was not statistically significant (0.637). There was no statistically significant difference between the two groups in general data such as gender, age, and body mass index (all 0.05), while there were statistically significant differences between the two groups in upper instrumented vertebrea (UIV) location and junctional area posterior ligamentous complex (PLC) injury (all <0.05). The results of univariate analysis showed that UIV location at T-T, junctional area PLC injury, preoperative coronal thoracic curve (TC), preoperative and final follow-up PJA, and preoperative and final follow-up pelvic incidence-lumbarlordosis (PI-LL) were correlated with postoperative PJK (=2.50, 5.37, 0.92, 1.12, 1.32, 1.06, 3.35, all <0.05). Multifactorial logistic regression analysis showed that UIV located at T-T (=2.346, 95%: 1.582-3.481, 0.001), junctional area PLC injury (=5.112, 95%: 1.283-20.418, 0.023) and last follow-up PI-LL (=1.826, 95%: 1.558-24.745, 0.012) were risk factors for the occurrence of postoperative PJK in children with Lenke type 5 AIS. Postoperative UIV fixation to the thoracolumbar segment, PLC injury in the junctional area and excessive postoperative PI-LL in children with Lenke type 5 AIS may be the risk factors for the occurrence of PJK after the operation. It is suggested that avoidance of UIV selection to the thoracolumbar segment, intraoperative protection of the PLC located near the UIV and restoration of a good PI-LL relationship may reduce the incidence of PJK.

摘要

探讨Lenke 5型青少年特发性脊柱侧凸(AIS)患儿后路脊柱融合术后近端交界性后凸(PJK)发生的相关危险因素。这是一项回顾性病例对照研究,纳入了2013年1月至2018年12月在西安交通大学附属红会医院接受全身麻醉下后路矫形手术的98例Lenke 5型AIS患儿的病历资料。其中男性23例,女性75例,平均年龄(14.5±2.2)岁(10 - 18岁)。根据末次随访时后路交界角(PJA)是否大于10°且较术前增加超过10°,将患者分为PJK组和非PJK组。采用单因素分析分析患儿一般资料与术后PJK发生的相关性。采用多因素logistic回归分析分析术后PJK的危险因素。PJK组35例,非PJK组63例。PJK组和非PJK组分别随访(35.6±7.3)个月和(36.4±7.5)个月,差异无统计学意义(0.637)。两组在性别、年龄、体重指数等一般资料方面差异无统计学意义(均P>0.05),而在上端椎(UIV)位置和交界区后方韧带复合体(PLC)损伤方面两组差异有统计学意义(均P<0.05)。单因素分析结果显示,UIV位于T - T、交界区PLC损伤、术前冠状面胸椎曲度(TC)、术前及末次随访时的PJA以及术前及末次随访时的骨盆入射角 - 腰椎前凸角(PI - LL)与术后PJK相关(P值分别为2.50、5.37、0.92、1.12、1.32、1.06、3.35,均P<0.05)。多因素logistic回归分析显示,UIV位于T - T(P = 2.346,95%CI:1.582 - 3.481,P = 0.001)、交界区PLC损伤(P = 5.112,95%CI:1.283 - 20.418,P = 0.023)和末次随访时的PI - LL(P = 1.826,95%CI:1.558 - 24.745,P = 0.012)是Lenke 5型AIS患儿术后PJK发生的危险因素。Lenke 5型AIS患儿术后UIV固定于胸腰段、交界区PLC损伤及术后PI - LL过大可能是术后PJK发生的危险因素。建议避免选择UIV至胸腰段、术中保护UIV附近的PLC以及恢复良好的PI - LL关系可能会降低PJK的发生率。

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