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苯二氮䓬类药物与术后谵妄:我们是否应该像现在这样谨慎?

Benzodiazepines and postoperative delirium: should we be as cautious as we are?

机构信息

Department of Critical Care, School of Medicine, University of Melbourne, Victoria, Australia; Department of Anaesthesia and Acute Pain Medicine, St. Vincent's Hospital Melbourne, Victoria, Australia; Department of Anesthesiology, Weill Cornell Medicine, New York, NY, USA.

Department of Anesthesiology, Weill Cornell Medicine, New York, NY, USA.

出版信息

Br J Anaesth. 2023 Oct;131(4):629-631. doi: 10.1016/j.bja.2023.07.004. Epub 2023 Aug 4.

Abstract

A recent systematic review and meta-analysis by Wang and colleagues in the British Journal of Anaesthesia calls into question the concept that perioperative benzodiazepine administration is associated with development of postoperative delirium in older individuals after anaesthesia and surgery. This editorial focuses on potential bias within the systematic review and addresses major concerns surrounding benzodiazepine use in the older perioperative population.

摘要

近期,英国《麻醉学杂志》刊登了一篇由 Wang 及其同事撰写的系统评价和荟萃分析,对围手术期苯二氮䓬类药物的使用与麻醉和手术后老年患者术后谵妄的发生之间存在相关性的这一概念提出了质疑。本文述评重点探讨了该系统评价中可能存在的偏倚,并就老年围手术期人群中使用苯二氮䓬类药物的主要关注点进行了讨论。

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