Gowda Prateek C, Dunlap Robert H, Ahlawat Shivani, Gross John M, Morris Carol D, Lyons Gray R
Russell H. Morgan Department of Radiology and Radiological Science, Division of Interventional Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Division of Musculoskeletal Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Skeletal Radiol. 2023 Dec;52(12):2497-2501. doi: 10.1007/s00256-023-04414-4. Epub 2023 Aug 7.
Chondromyxoid fibroma is a rare, benign tumor of the bone with excellent prognosis but a high rate of recurrence. We report a patient presenting with pain and a history of chondromyxoid fibroma of the distal left femur previously treated with multiple prior curettage and bone graft procedures. Magnetic resonance imaging and histopathology indicated a recurrence of tumor. Due to the small size of the tumor recurrence and challenges associated with prior open surgery, the patient underwent cryoablation of the lesion with computed tomography guidance. Follow-up 18 months later indicated a resolution of pain and improvement on magnetic resonance imaging, and no concerns after 20 months. To our knowledge, this is the first reported case of chondromyxoid fibroma treated with cryoablation. This case suggests cryoablation could be considered in the setting of recurrent chondromyxoid fibroma for local tumor control.
软骨黏液样纤维瘤是一种罕见的骨良性肿瘤，预后良好，但复发率高。我们报告了一名患者，该患者因疼痛就诊，既往有左股骨远端软骨黏液样纤维瘤病史，曾接受过多次刮除术和骨移植手术。磁共振成像和组织病理学检查提示肿瘤复发。由于肿瘤复发灶较小且既往开放手术存在挑战，该患者在计算机断层扫描引导下接受了病变的冷冻消融治疗。18个月后的随访显示疼痛缓解，磁共振成像表现改善，20个月后无异常。据我们所知，这是首例报道的采用冷冻消融治疗软骨黏液样纤维瘤的病例。该病例提示，对于复发性软骨黏液样纤维瘤，可考虑采用冷冻消融进行局部肿瘤控制。
