Department of Cardiology, Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, P.O. Box 1998734383, Tehran, Iran.
Cardiovascular Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
J Med Case Rep. 2023 Aug 7;17(1):334. doi: 10.1186/s13256-023-04070-1.
Nonbacterial thrombotic endocarditis is a rare complication of prothrombotic states such as neoplasms that can cause valvular dysfunction and life-threatening complications. Nonbacterial thrombotic endocarditis usually affects the left-sided valves; however, only a minority of cases involving the tricuspid valve have been reported in medical literature.
The current report describes trivalvular involvement by nonbacterial thrombotic endocarditis in a 54-year-old Azeri female patient with metastatic colorectal carcinoma. This case underlines the necessity of evaluating nonbacterial thrombotic endocarditis as a possible consequence in cancer patients. When thromboembolic events are found in the presence of a hypercoagulable state (such as malignancy) and no growth on blood cultures, nonbacterial thrombotic endocarditis could be suspected as the cause.
It is critical to achieve early diagnosis in such a setting to initiate treatment plans and prevent further complications rapidly.
非细菌性血栓性心内膜炎是一种罕见的促血栓状态的并发症,如肿瘤,可导致瓣膜功能障碍和危及生命的并发症。非细菌性血栓性心内膜炎通常影响左侧瓣膜;然而,只有少数涉及三尖瓣的病例在医学文献中有报道。
本报告描述了一名 54 岁阿塞拜疆女性转移性结直肠癌患者的三尖瓣非细菌性血栓性心内膜炎。该病例强调了在癌症患者中评估非细菌性血栓性心内膜炎作为一种可能后果的必要性。当存在高凝状态(如恶性肿瘤)且血培养无生长时,可怀疑血栓栓塞事件的原因是非细菌性血栓性心内膜炎。
在这种情况下,早期诊断至关重要,以便迅速启动治疗计划并预防进一步的并发症。