Ciavarella Domenico, Campobasso Alessandra, Cazzolla Angela Pia, Suriano Carmela, Lo Muzio Eleonora, Guida Laura, Salcuni Fabio, Laurenziello Michele, Illuzzi Gaetano, Burlon Giuseppe, Tepedino Michele
Department of Clinical and Experimental Medicine, Dental School of Foggia, University of Foggia, Foggia, Italy.
Department of Orthodontic, University of Ferrara, Ferrara, Italy.
Cranio. 2023 Aug 6:1-8. doi: 10.1080/08869634.2023.2242061.
The Mandibular Advancement Device (MAD) is actually recommended for the treatment of Obstructive Sleep Apnea (OSA) with mild or moderate severity. The present study evaluated the effects of a fully customizable MAD-type device (It Makes You Sleep, IMYS), in patients with moderate-to-severe OSA.
Twenty-nine patients (15 men and 14 women; mean age 62, SD ±10 years) were retrospectively enrolled. Home Sleep Apnea Testing ;(HSAT) was performed for all patients at baseline (T0) and after three months (T1) of IMYS therapy. The analyzed respiratory parameters were: Apnea-Hypopnea Index (AHI), Oxygen Desaturation Index (ODI), Minimum Oxygen Saturation (minSO2) and Medium Oxygen Saturation (medSO2).
From T0 to T1, a significant reduction of AHI and ODI was reported, as well as a significant increase of minSO2 and medSO2.
The IMYS device could be an effective MAD appliance for treating moderate-to-severe OSA.
下颌前移装置（MAD）实际上被推荐用于治疗轻度或中度阻塞性睡眠呼吸暂停（OSA）。本研究评估了一种完全可定制的MAD型装置（“助眠宝”，IMYS）对中重度OSA患者的疗效。
回顾性纳入29例患者（15例男性和14例女性；平均年龄62岁，标准差±10岁）。在基线时（T0）以及IMYS治疗三个月后（T1），对所有患者进行家庭睡眠呼吸暂停测试（HSAT）。分析的呼吸参数包括：呼吸暂停低通气指数（AHI）、氧饱和度下降指数（ODI）、最低氧饱和度（minSO2）和平均氧饱和度（medSO2）。
从T0到T1，AHI和ODI显著降低，minSO2和medSO2显著升高。
IMYS装置可能是治疗中重度OSA的一种有效MAD器具。
