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病例报告:小脑经颅直流电刺激对脑卒中后双语失语症的影响

Case report: the effects of cerebellar tDCS in bilingual post-stroke aphasia.

作者信息

Coemans Silke, Struys Esli, Tsapkini Kyrana, Paquier Philippe, Vandenborre Dorien, Keulen Stefanie

机构信息

Brussels Centre for Language Studies (BCLS), Vrije Universiteit Brussels, Brussels, Belgium.

Center for Neurosciences (C4N), Vrije Universiteit Brussels, Brussels, Belgium.

出版信息

Front Hum Neurosci. 2023 Jul 20;17:1173178. doi: 10.3389/fnhum.2023.1173178. eCollection 2023.

Abstract

Transcranial Direct Current Stimulation may be a useful neuromodulation tool for enhancing the effects of speech and language therapy in people with aphasia, but research so far has focused on monolinguals. We present the effects of 9 sessions of anodal cerebellar tDCS (ctDCS) coupled with language therapy in a bilingual patient with chronic post-stroke aphasia caused by left frontal ischemia, in a double-blind, sham-controlled within-subject design. Language therapy was provided in his second language (L2). Both sham and anodal treatment improved trained picture naming in the treated language (L2), while anodal ctDCS in addition improved picture naming of untrained items in L2 and his first language, L1. Picture description improved in L2 and L1 after anodal ctDCS, but not after sham.

摘要

经颅直流电刺激可能是一种有用的神经调节工具,可增强失语症患者言语和语言治疗的效果,但迄今为止的研究主要集中在单语者身上。我们采用双盲、假对照的受试者内设计,展示了9次阳极小脑经颅直流电刺激(ctDCS)联合语言治疗对一名因左侧额叶缺血导致慢性中风后失语的双语患者的效果。语言治疗采用他的第二语言(L2)进行。假刺激和阳极刺激治疗均改善了治疗语言(L2)中训练过的图片命名,而阳极ctDCS还改善了L2和其第一语言L1中未训练项目的图片命名。阳极ctDCS后,L2和L1中的图片描述能力有所改善,但假刺激后未改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2340/10398340/2a5582814ff6/fnhum-17-1173178-g001.jpg

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