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既往非肝切除术腹部手术并未增加肝细胞癌腹腔镜肝切除术的难度:100例连续患者的病例对照研究

Previous nonhepatectomy abdominal surgery did not increase the difficulty in laparoscopic hepatectomy for hepatocellular carcinoma: A case-control study in 100 consecutive patients.

作者信息

Lee Yi-Hsuan, Lin Hsiu-Hsien, Kuo Tsai-Ling, Lee Ming-Che, Chen Yen-Cheng

机构信息

Division of General Surgery, Department of Surgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.

Department of Nursing, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.

出版信息

Tzu Chi Med J. 2023 Feb 13;35(3):247-252. doi: 10.4103/tcmj.tcmj_293_22. eCollection 2023 Jul-Sep.

DOI:10.4103/tcmj.tcmj_293_22
PMID:37545796
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10399838/
Abstract

OBJECTIVES

Laparoscopic hepatectomy (LH) is still technically challenging for patients with previous nonhepatectomy abdominal surgery (AS). Therefore, this study aimed to assess the difficulty of performing LH for patients with hepatocellular carcinoma (HCC) and a history of nonhepatectomy AS during the initial developing period of LH.

MATERIALS AND METHODS

The retrospective study enrolled patients who were newly diagnosed with HCC receiving LH from January 2013 to June 2021. Demographic characteristics, perioperative variables, and surgical complications were prospectively collected.

RESULTS

One hundred patients were reviewed consecutively, comprising 23 in the AS group and 77 in the non-AS group. No significant differences were observed in median IWATE score (5 vs. 5, = 0.194), operative time (219 vs. 200 min, = 0.609), blood loss (100.0 vs. 200.0 mL, = 0.734), transfusion rate (4.3% vs. 10.4%, = 0.374), duration of parenchyma transection (90.0 vs. 72.4 min, = 0.673), and mean nonparenchymal transection time (191.0 vs. 125.0 min, = 0.228), without increasing the conversion rate (0.0% vs. 3.9%, = 0.336), postoperative complications (30.3% vs. 33.8%, = 0.488), and postoperative hospital stay (6 vs. 7 days, = 0.060) in AS group and non-AS groups.

CONCLUSION

History of previous nonhepatectomy AS can lead to longer nonparenchymal transection time instead of conversion and did not increase the difficulty. Prolonged nonparenchymal transection time did not increase the surgical complications, prolong the postoperative hospital stay, and compromise the survival outcomes.

摘要

目的

对于既往有非肝切除腹部手术(AS)史的患者,腹腔镜肝切除术(LH)在技术上仍具有挑战性。因此,本研究旨在评估在LH初始发展阶段,肝细胞癌(HCC)且有非肝切除AS史的患者进行LH的难度。

材料与方法

这项回顾性研究纳入了2013年1月至2021年6月新诊断为HCC并接受LH的患者。前瞻性收集人口统计学特征、围手术期变量和手术并发症。

结果

连续审查了100例患者,其中AS组23例,非AS组77例。两组在中位岩手评分(5 vs. 5,P = 0.194)、手术时间(219 vs. 200分钟,P = 0.609)、失血量(100.0 vs. 200.0毫升,P = 0.734)、输血率(4.3% vs. 10.4%,P = 0.374)、实质切开时间(90.0 vs. 72.4分钟,P = 0.673)和平均非实质切开时间(191.0 vs. 125.0分钟,P = 0.228)方面均未观察到显著差异,且未增加AS组和非AS组的中转率(0.0% vs. 3.9%,P = 0.336)、术后并发症(30.3% vs. 33.8%,P = 0.488)以及术后住院时间(6 vs. 7天,P = 0.060)。

结论

既往非肝切除AS史可导致非实质切开时间延长,但不会导致中转,且不会增加手术难度。非实质切开时间延长并未增加手术并发症、延长术后住院时间以及影响生存结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5349/10399838/d44c72d20874/TCMJ-35-247-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5349/10399838/db01075bead1/TCMJ-35-247-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5349/10399838/d44c72d20874/TCMJ-35-247-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5349/10399838/db01075bead1/TCMJ-35-247-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5349/10399838/d44c72d20874/TCMJ-35-247-g002.jpg

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本文引用的文献

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J Hepatol. 2022 Mar;76(3):681-693. doi: 10.1016/j.jhep.2021.11.018. Epub 2021 Nov 19.
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Predictors of 90-Day Mortality following Hepatic Resection for Hepatocellular Carcinoma.肝细胞癌肝切除术后90天死亡率的预测因素
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Effect of Previous Abdominal Surgery on Laparoscopic Liver Resection: Analysis of Feasibility and Risk Factors for Conversion.
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What has changed after the Morioka consensus conference 2014 on laparoscopic liver resection?2014年盛冈腹腔镜肝切除术共识会议之后有哪些变化?
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Is Laparoscopic Hepatectomy a Safe, Feasible Procedure in Patients with a Previous Upper Abdominal Surgery?对于曾接受过上腹部手术的患者,腹腔镜肝切除术是一种安全、可行的手术吗?
Chin Med J (Engl). 2016 Feb 20;129(4):399-404. doi: 10.4103/0366-6999.176068.
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