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在乌干达北部的一家大型艾滋病诊所接受抗逆转录病毒治疗的关键人群中,高危性行为的高发率。

High prevalence of risky sexual behaviour among key populations receiving antiretroviral therapy at a large HIV clinic in northern Uganda.

机构信息

The AIDS Support Organization (TASO), Gulu Centre of Clinical Excellence, P. O. BOX 347, Gulu City.

Department of Community Health, Faculty of Medicine, Mbarara University of Science and Technology (MUST), P.O.BOX, 1410, Mbarara City.

出版信息

Afr Health Sci. 2023 Mar;23(1):362-372. doi: 10.4314/ahs.v23i1.38.

Abstract

BACKGROUND

Risky sexual behaviour (RSB) among key populations pose a significant risk of human immunodeficiency virus (HIV) infection but remains understudied.

OBJECTIVES

We assessed the prevalence and factors associated with RSB among key populations living with HIV (KPLHIV) in the post-conflict region of northern Uganda.

METHODS

We designed a cross-sectional study using secondary data, with the outcome as RSB defined as having multiple sexual partners, or condomless sex in the past 3 months, or sexual intercourse with a commercial sex worker in the past 3 months, or sexual intercourse under the influence of substance use in the past 3 months. We used modified Poisson regression to determine factors associated with RSB, reported as adjusted risk ratio (aRR) with 95% confidence interval (CI).

RESULTS

We studied 165 participants and 122 (73.9%) reported RSB and this was more likely among heterosexual females (aRR, 2.39; 95% CI, 1.54-3.71), the married (aRR, 1.92; 95% CI, 1.42-2.49) or separated participants (aRR, 1.47; 95% CI, 1.21-1.79), and transgender persons (aRR, 3.71; 95% CI, 2.05-6.71).

CONCLUSIONS

RSB is highly prevalent among KPLHIV in northern Uganda so they should be targeted with HIV prevention and behavioural interventions to prevent potential HIV transmission to the general population.

摘要

背景

关键人群中的高危性行为(RSB)对人类免疫缺陷病毒(HIV)感染构成重大风险,但研究不足。

目的

我们评估了乌干达北部冲突后地区 HIV 感染者中的关键人群(KPLHIV)中高危性行为的流行情况及其相关因素。

方法

我们采用横断面研究设计,利用二次数据,将 RSB 定义为过去 3 个月内有多个性伴侣、无保护性行为、与性工作者发生性行为或在过去 3 个月内因物质使用而发生性行为。我们使用修正泊松回归来确定与 RSB 相关的因素,报告为调整后的风险比(aRR)及其 95%置信区间(CI)。

结果

我们研究了 165 名参与者,其中 122 名(73.9%)报告了 RSB,异性恋女性(aRR,2.39;95%CI,1.54-3.71)、已婚(aRR,1.92;95%CI,1.42-2.49)或分居参与者(aRR,1.47;95%CI,1.21-1.79)以及跨性别者(aRR,3.71;95%CI,2.05-6.71)发生 RSB 的可能性更高。

结论

乌干达北部的 KPLHIV 中 RSB 非常普遍,因此应针对他们开展 HIV 预防和行为干预措施,以防止潜在的 HIV 向普通人群传播。

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