Telesforo P, Rosenberg R
Quad Sclavo Diagn. 1978 Sep;15(3):365-72.
The levels of PHI are evaluated in 94 patients, who are classified by histological, scintigraphycal, radiological, biochemical and clinical test in: 16 patients, who suffer from some premalignant lesions of breast and uterus, 15 patients, who suffer from cancer of breast without metastases, 20 patients who suffer from cancer of breast with metastases, 18 patients who suffer from with cancer of uterus without metastases, 25 patients who suffer from cancer of uterus with metastases. The PHI activity is also evaluated in relation to the activity of other enzymes (LDH, AIP, G-GT). It has been revealed that: a) the PHI activity keeps within limits of normal value in patients who suffer from some pre-malignant lesions; b) all the patients suffer from cancer of breast without metastases show normal levels of PHI; c) in the patients with cancer of breast with metastases: 5 patients show normal levels of PHI, 5 patients show levels of PHI within limits, certainly 10 patients show pathological levels; d) in patients with cancer of uterus without metastases the value of enzymes results pathological in 6 patients, 6 patients show levels of PHI within limits that are above average and 6 patients show normal levels of PHI; e) the value of PHI always results high in patients with cancer of uterus with metastases.
对94例患者的PHI水平进行了评估,这些患者通过组织学、闪烁扫描、放射学、生化和临床检查分为以下几类:16例患有乳腺和子宫某些癌前病变的患者;15例无转移的乳腺癌患者;20例有转移的乳腺癌患者;18例无转移的子宫癌患者;25例有转移的子宫癌患者。还根据其他酶(LDH、AIP、G-GT)的活性对PHI活性进行了评估。结果显示:a)患有某些癌前病变的患者,其PHI活性保持在正常值范围内;b)所有无转移的乳腺癌患者PHI水平均正常;c)有转移的乳腺癌患者中:5例PHI水平正常,5例PHI水平在正常范围内,10例PHI水平呈病理性;d)无转移的子宫癌患者中,6例酶值呈病理性,6例PHI水平高于平均正常范围,6例PHI水平正常;e)有转移的子宫癌患者中,PHI值始终偏高。