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运动诱发的室内梯度作为心脏性猝死的潜在原因

Exercise-Induced Intraventricular Gradients As a Potential Cause of Sudden Cardiac Death.

作者信息

Cotrim Carlos A, Cotrim Nuno, Guardado Jorge H, Baquero Luis

机构信息

Heart Center, Hospital da Cruz Vermelha, Lisboa, PRT.

Cardiology, Unidade Cardiovascular de Riachos, Riachos, PRT.

出版信息

Cureus. 2023 Jul 5;15(7):e41408. doi: 10.7759/cureus.41408. eCollection 2023 Jul.

DOI:10.7759/cureus.41408
PMID:37546084
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10402846/
Abstract

A 16-year-old boy reported an episode of dizziness related to intense training six months before an episode of aborted sudden death. The screening required for competitive sports practice was normal. There were no personal or familial antecedents of sudden death or heart disease. After winning a triathlon competition, he experienced a cardiac arrest episode. He received defibrillation with the return of spontaneous circulation. A medical evaluation that included electrocardiogram (ECG) and echocardiogram had normal results. A complete study including cardiac MRI, coronary CT angiography, a genetic study for heart disease, the flecainide test, and a stress echocardiogram with ergometrine was done, and all results were normal. During a Holter ECG and exercise stress echo, isolated premature ventricular complexes were detected. During the effort treadmill stress echocardiogram, the athlete developed a significant intraventricular obstruction with an end-systolic peak, without systolic anterior movement of the mitral valve, which disappeared in the first minute of the recovery. We highlight the possible cause-effect relation between the events.

摘要

一名16岁男孩在猝死未遂发作前六个月报告了一次与高强度训练相关的头晕发作。竞技体育训练所需的筛查结果正常。没有猝死或心脏病的个人或家族病史。在赢得一场铁人三项比赛后,他经历了一次心脏骤停发作。他接受了除颤,恢复了自主循环。包括心电图(ECG)和超声心动图在内的医学评估结果正常。进行了包括心脏MRI、冠状动脉CT血管造影、心脏病基因研究、氟卡尼试验以及麦角新碱负荷超声心动图在内的全面检查,所有结果均正常。在动态心电图和运动负荷超声心动图检查期间,检测到孤立性室性早搏。在运动平板负荷超声心动图检查期间,该运动员出现了明显的心室梗阻,收缩末期达到峰值,二尖瓣无收缩期前向运动,在恢复的第一分钟消失。我们强调了这些事件之间可能的因果关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a60/10402846/9225a3e9a38a/cureus-0015-00000041408-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a60/10402846/3d9b6fc8925f/cureus-0015-00000041408-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a60/10402846/9225a3e9a38a/cureus-0015-00000041408-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a60/10402846/3d9b6fc8925f/cureus-0015-00000041408-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a60/10402846/9225a3e9a38a/cureus-0015-00000041408-i02.jpg

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本文引用的文献

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The Clinical Use of Stress Echocardiography in Non-Ischaemic Heart Disease: Recommendations from the European Association of Cardiovascular Imaging and the American Society of Echocardiography.应激超声心动图在非缺血性心脏病中的临床应用:欧洲心血管影像学会和美国超声心动图学会的建议
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Elevated left ventricular outflow tract velocities on exercise stress echocardiography may be a normal physiologic response in healthy youth.运动超声心动图显示左心室流出道速度升高可能是健康青年的正常生理反应。
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Stress-induced intraventricular gradients in symptomatic athletes during upright exercise continuous wave Doppler echocardiography.直立运动时连续波多普勒超声心动图检测有症状运动员应激性心室内梯度。
Am J Cardiol. 2010 Dec 15;106(12):1808-12. doi: 10.1016/j.amjcard.2010.07.053.
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Efficacy of beta-blocker therapy in symptomatic athletes with exercise-induced intra-ventricular gradients.β受体阻滞剂治疗有症状的运动诱发心室梯度运动员的疗效。
Cardiovasc Ultrasound. 2010 Sep 2;8:38. doi: 10.1186/1476-7120-8-38.
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Exercise-induced intra-ventricular gradients as a frequent potential cause of myocardial ischemia in cardiac syndrome X patients.运动诱发的室内梯度作为心脏综合征X患者心肌缺血的常见潜在原因。
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