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胰岛素瘤患者功能性生长抑素受体的术前检测

Preoperative detection of functional somatostatin receptors in a patient with an insulinoma.

作者信息

Oguni Kohei, Fukushima Shinnosuke, Yamamoto Yukichika, Hasegawa Kou, Hagiya Hideharu, Inoshita Naoko, Otsuka Fumio

机构信息

Department of General Medicine Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan.

Department of Pathology Moriyama Memorial Hospital Tokyo Japan.

出版信息

Clin Case Rep. 2023 Aug 2;11(8):e7771. doi: 10.1002/ccr3.7771. eCollection 2023 Aug.

Abstract

Octreotide is used in patients with insulinomas to treat hypoglycemia, and somatostatin receptor (SSTR) 2 expression is important for its efficacy. We report a case of insulinoma in a 50-year-old woman that responded to an octreotide test, showed accumulation in somatostatin scintigraphy, and was positive for SSTR2A on immunostaining.

摘要

奥曲肽用于胰岛素瘤患者治疗低血糖,生长抑素受体(SSTR)2的表达对其疗效至关重要。我们报告一例50岁女性胰岛素瘤病例,该病例对奥曲肽试验有反应,在生长抑素闪烁扫描中显示有积聚,免疫染色显示SSTR2A呈阳性。

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