Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, South Korea.
Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, South Korea.
Obesity (Silver Spring). 2023 Sep;31(9):2430-2439. doi: 10.1002/oby.23853. Epub 2023 Aug 7.
This study evaluated the potential role of overall diet quality in the associations between ultraprocessed food (UPF) consumption and adiposity indicators among Korean adults.
Baseline data of participants (n = 4331) of the Cardiovascular and Metabolic Diseases Etiology Research Center (CMERC) cohort study were obtained. Dietary information was collected by a validated food frequency questionnaire. UPF was defined using the NOVA classification. Overall diet quality was assessed using the Korean Healthy Eating Index. Adiposity indicators included BMI, waist circumference, percentage body fat by bioimpedance, and visceral fat mass by whole-body dual-energy x-ray absorptiometry. Mediation analysis after adjustment for potential confounders was performed.
UPF intake was associated with higher adiposity indicators after adjustment for confounders. The mediating effect of the Korean Healthy Eating Index on the relationship between UPF consumption and each adiposity indicator was 35.6% (95% CI: 4.9% to 255.9%) for BMI, 38.3% (17.9% to 132.1%) for waist circumference, 40.2% (8.3% to 259.4%) for percentage body fat, and 60.7% (-396.4% to 662.7%) for visceral fat mass.
UPF consumption was positively associated with adiposity indicators, which were partially attributed to the overall diet quality. Further studies are needed to better understand the causal mechanisms of these associations.
本研究评估了整体饮食质量在超加工食品（UPF）消费与韩国成年人肥胖指标之间关联中的潜在作用。
本研究获得了心血管和代谢疾病病因学研究中心（CMERC）队列研究参与者（n=4331）的基线数据。通过验证后的食物频率问卷收集饮食信息。使用 NOVA 分类法定义 UPF。使用韩国健康饮食指数评估整体饮食质量。肥胖指标包括 BMI、腰围、生物阻抗法测定的体脂肪百分比和全身双能 X 射线吸收仪测定的内脏脂肪量。在调整潜在混杂因素后进行中介分析。
调整混杂因素后，UPF 摄入与更高的肥胖指标相关。韩国健康饮食指数在 UPF 消费与每个肥胖指标之间的关系中的中介效应为 BMI（35.6%，95%CI：4.9%至 255.9%）、腰围（38.3%，17.9%至 132.1%）、体脂肪百分比（40.2%，8.3%至 259.4%）和内脏脂肪量（60.7%，-396.4%至 662.7%）。
UPF 消费与肥胖指标呈正相关，这部分归因于整体饮食质量。需要进一步研究以更好地理解这些关联的因果机制。
