钆喷酸葡胺通过MRGPRX2诱导不依赖免疫球蛋白的人肥大细胞活化。 - Suppr | 超能文献

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Meglumine gadoterate induces immunoglobulin-independent human mast cell activation via MRGPRX2.钆喷酸葡胺通过MRGPRX2诱导不依赖免疫球蛋白的人肥大细胞活化。

Allergy. 2023 Dec;78(12):3255-3258. doi: 10.1111/all.15847. Epub 2023 Aug 7.

2

Human Mast Cell Line HMC1 Expresses Functional Mas-Related G-Protein Coupled Receptor 2.人肥大细胞系 HMC1 表达功能性 Mas 相关 G 蛋白偶联受体 2。

Front Immunol. 2021 Mar 15;12:625284. doi: 10.3389/fimmu.2021.625284. eCollection 2021.

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Inflamed Ulcerative Colitis Regions Associated With MRGPRX2-Mediated Mast Cell Degranulation and Cell Activation Modules, Defining a New Therapeutic Target.炎症性溃疡性结肠炎区域与 MRGPRX2 介导的肥大细胞脱颗粒和细胞激活模块相关，定义了一个新的治疗靶点。

Gastroenterology. 2021 Apr;160(5):1709-1724. doi: 10.1053/j.gastro.2020.12.076. Epub 2021 Jan 6.

4

Mast cell degranulation via MRGPRX2 by isolated human albumin fragments.通过分离的人白蛋白片段通过 MRGPRX2 脱颗粒化肥大细胞。

Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt A):2530-2534. doi: 10.1016/j.bbagen.2017.08.013. Epub 2017 Aug 24.

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MRGPRX2 activation as a rapid, high-throughput mechanistic-based approach for detecting peptide-mediated human mast cell degranulation liabilities.MRGPRX2 激活作为一种快速、高通量的基于机制的方法，用于检测肽介导的人肥大细胞脱粒的潜在风险。

J Immunotoxicol. 2020 Dec;17(1):110-121. doi: 10.1080/1547691X.2020.1757793.

6

Novel Insights on MRGPRX2-Mediated Hypersensitivity to Neuromuscular Blocking Agents And Fluoroquinolones.MRGPRX2 介导的神经肌肉阻滞剂和氟喹诺酮类药物过敏的新见解。

Front Immunol. 2021 Jul 27;12:668962. doi: 10.3389/fimmu.2021.668962. eCollection 2021.

7

Caffeic acid phenethyl ester inhibits pseudo-allergic reactions via inhibition of MRGPRX2/MrgprB2-dependent mast cell degranulation.咖啡酸苯乙酯通过抑制MRGPRX2/MrgprB2依赖性肥大细胞脱颗粒来抑制类过敏反应。

Arch Pharm Res. 2022 Sep;45(9):644-657. doi: 10.1007/s12272-022-01405-2. Epub 2022 Oct 2.

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Differential Regulation of Mas-Related G Protein-Coupled Receptor X2-Mediated Mast Cell Degranulation by Antimicrobial Host Defense Peptides and Porphyromonas gingivalis Lipopolysaccharide.抗菌宿主防御肽和牙龈卟啉单胞菌脂多糖对Mas相关G蛋白偶联受体X2介导的肥大细胞脱颗粒的差异调节

Infect Immun. 2017 Sep 20;85(10). doi: 10.1128/IAI.00246-17. Print 2017 Oct.

9

Typical antimicrobials induce mast cell degranulation and anaphylactoid reactions via MRGPRX2 and its murine homologue MRGPRB2.典型的抗菌药物通过MRGPRX2及其小鼠同源物MRGPRB2诱导肥大细胞脱颗粒和类过敏反应。

Eur J Immunol. 2017 Nov;47(11):1949-1958. doi: 10.1002/eji.201746951. Epub 2017 Sep 4.

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Endogenous protein and enzyme fragments induce immunoglobulin E-independent activation of mast cells via a G protein-coupled receptor, MRGPRX2.内源性蛋白质和酶片段通过G蛋白偶联受体MRGPRX2诱导肥大细胞的免疫球蛋白E非依赖性激活。

Scand J Immunol. 2018 May;87(5):e12655. doi: 10.1111/sji.12655. Epub 2018 Apr 2.

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