Clin Nephrol. 2023 Oct;100(4):177-180. doi: 10.5414/CN111115.
Sarcoidosis is a multisystem inflammatory disease that most frequently affects the lungs, lymph nodes, eyes, and skin. Renal involvement is clinically rare. We describe a 72-year-old male who presented with chronic kidney disease and elevated serum calcium and angiotensin-converting enzyme. Renal biopsy pathology showed chronic granulomatous interstitial nephritis. Renal function was significantly improved after glucocorticoid therapy. This case emphasizes that chronic kidney disease and hypercalcemia can be clues for renal sarcoidosis. Early renal biopsy and projective treatment is beneficial for renal outcome.
结节病是一种多系统炎症性疾病，最常累及肺部、淋巴结、眼睛和皮肤。肾脏受累在临床上较为罕见。我们描述了一名 72 岁男性，他因慢性肾脏病和血清钙及血管紧张素转换酶升高而就诊。肾活检病理显示慢性肉芽肿性间质性肾炎。糖皮质激素治疗后肾功能显著改善。本病例强调慢性肾脏病和高钙血症可能是肾结节病的线索。早期肾活检和靶向治疗有利于肾脏结局。
