七年调查中，从业者报告的使用障碍、成本考虑因素和即时检测性传播感染的优先事项的异质性。

Heterogeneity in practitioner-reported barriers to use, cost considerations and priorities for point of care sexually transmitted infection tests on surveys across seven years.

机构信息

Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

出版信息

Int J STD AIDS. 2023 Dec;34(14):1012-1017. doi: 10.1177/09564624231194375. Epub 2023 Aug 7.

DOI:10.1177/09564624231194375

PMID:37548593

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11156494/

Abstract

BACKGROUND

Point of care diagnostic tests (POCTs) for sexually transmitted infections (STIs) have the potential to improve STI care worldwide. However, barriers to adoption, cost considerations and practitioner priorities may not be uniform globally and over time. We conducted two surveys, 7 years apart, among members of the International Union Against Sexually Transmitted Infections (IUSTI), and compare results here.

METHODS

Surveys were given to members attending two IUSTI conferences in 2012 (Australia) and 2019 (Estonia). Descriptive analyses were performed and chi-square or Fisher's exact tests conducted.

RESULTS

Amongst = 190 participants in 2012 and = 166 in 2019, 61% in 2012 and 77% in 2019 were from high-income countries (HICs). In 2012, 84% of respondents from low- and middle-income countries (LMICs) and 70% from HICs thought cost of test was more important than amount of reimbursement. Trends were similar in 2019. In 2012, unreliability was considered the most important barrier to POCT use by all groups, followed by being laboratory-driven and complexity. In 2019, time frame was considered most important, followed by unreliability and being laboratory-driven. In 2012, the top priority for POCT development among LMIC respondents was early HIV seroconversion (31%), versus chlamydia (57%) for HICs. In 2019, chlamydia remained top priority for HICs (40%), followed by early HIV seroconversion (19%) and gonorrhea (17%); top priorities for LMICs were chlamydia (26%), HPV (24%), and early HIV seroconversion (21%).

CONCLUSIONS

Practitioner priorities for STI POCTs may be shifting. Cost may be critical to adoption in all settings. Larger studies are needed to verify findings.

摘要

背景

即时检测（POCT）在性传播感染（STI）方面具有改善全球 STI 护理的潜力。然而，采用的障碍、成本考虑因素和从业者的优先事项在全球范围内可能并不统一，而且随着时间的推移也会发生变化。我们在相隔 7 年的时间里，分别在国际性传播感染学会（IUSTI）的两次会议上对成员进行了两次调查，并在此处比较结果。

方法

我们对 2012 年（澳大利亚）和 2019 年（爱沙尼亚）IUSTI 两次会议上的成员进行了调查。进行了描述性分析，并进行了卡方检验或 Fisher 确切检验。

结果

在 2012 年的 190 名参与者和 2019 年的 166 名参与者中，2012 年有 61%和 2019 年有 77%来自高收入国家（HICs）。2012 年，来自中低收入国家（LMICs）的 84%和 HICs 的 70%的受访者认为检测成本比报销金额更重要。2019 年的趋势相似。2012 年，所有群体都认为不可靠性是 POCT 使用的最重要障碍，其次是实验室驱动和复杂性。2019 年，时间框架被认为是最重要的，其次是不可靠性和实验室驱动。2012 年，LMIC 受访者对 POCT 发展的首要任务是早期 HIV 血清转换（31%），而 HIC 是衣原体（57%）。2019 年，衣原体仍然是 HIC 的首要任务（40%），其次是早期 HIV 血清转换（19%）和淋病（17%）；LMIC 的首要任务是衣原体（26%）、HPV（24%）和早期 HIV 血清转换（21%）。