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坚持使用支撑性阴道子宫托治疗盆腔器官脱垂:一项对 1371 名女性进行的回顾性研究。

Adherence to support pessary in the treatment of pelvic organ prolapse: a retrospective study conducted among 1,371 women.

机构信息

Medical Faculty, University of Southern Denmark, 55 Campusvej, 5230, Odense, Denmark.

Department of Gynecology and Obstetrics, Odense University Hospital, Odense, Denmark.

出版信息

Int Urogynecol J. 2024 Jan;35(1):69-75. doi: 10.1007/s00192-023-05616-z. Epub 2023 Aug 7.

DOI:10.1007/s00192-023-05616-z
PMID:37548745
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10810921/
Abstract

INTRODUCTION AND HYPOTHESIS

The objective was to investigate the adherence to pessary treatment in women with pelvic organ prolapse (POP) who were found eligible for this treatment by the urogynecologist, at the first visit at the Department of Gynecology and Obstetrics, Odense University Hospital.

METHODS

Data were extracted from the women's medical records. Frequency tabulations were performed to describe the women's reasons for pessary discontinuation by age group. Binominal logistic regression analysis was conducted to investigate how women's age, POP characteristics, urogynecological history, and their pessary experience and management were associated with continued pessary use.

RESULTS

This study included 1,371 women treated with support pessary. Of these, 850 women continued pessary treatment and 521 women underwent surgical treatment. A history of hysterectomy (OR: 0.68, 95% CI: 0.51-0.90, p = 0.008), urinary incontinence (OR: 0.71, 95% CI: 0.56-0.89, p = 0.003), and previous pessary use (OR: 0.75, 95% CI: 0.56-0.99, p = 0.047) were significant factors associated with discontinuation. Further, women aged 81-99 years were significantly more likely to continue pessary treatment (OR: 1.77, 95% CI: 1.15-2.74, p = 0.009). "POP surgery," "prolapse stage," and "prolapse predominant compartment" were not associated with discontinuation. Approximately 38% of women aged 26-54 years discontinued owing to personal preference.

CONCLUSIONS

Hysterectomy, incontinence, and previous pessary use are significant predictors of pessary discontinuation. Increasing age is significantly associated with pessary continuation.

摘要

介绍和假设

目的是调查在奥登塞大学医院妇产科首次就诊时,经泌尿科医生评估适合使用阴道子宫托治疗的盆腔器官脱垂(POP)女性的阴道子宫托治疗依从性。

方法

从女性的病历中提取数据。按年龄组对女性停止使用子宫托的原因进行频数描述。采用二项逻辑回归分析,研究女性年龄、POP 特征、泌尿科病史以及阴道子宫托使用和管理经验与继续使用阴道子宫托之间的关系。

结果

本研究共纳入 1371 名接受支撑性阴道子宫托治疗的女性。其中,850 名女性继续阴道子宫托治疗,521 名女性接受手术治疗。既往子宫切除术(OR:0.68,95%CI:0.51-0.90,p=0.008)、尿失禁(OR:0.71,95%CI:0.56-0.89,p=0.003)和既往使用阴道子宫托(OR:0.75,95%CI:0.56-0.99,p=0.047)是与停止使用相关的显著因素。此外,81-99 岁的女性继续阴道子宫托治疗的可能性显著更高(OR:1.77,95%CI:1.15-2.74,p=0.009)。“POP 手术”、“脱垂分期”和“脱垂主要部位”与停止使用无关。约 38%的 26-54 岁女性因个人偏好而停止使用。

结论

子宫切除术、尿失禁和既往使用阴道子宫托是阴道子宫托停止使用的重要预测因素。年龄增长与继续使用阴道子宫托显著相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b63/10810921/3f4cbff7e008/192_2023_5616_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b63/10810921/3f4cbff7e008/192_2023_5616_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b63/10810921/3f4cbff7e008/192_2023_5616_Fig1_HTML.jpg

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Clinical and cost-effectiveness of vaginal pessary self-management compared to clinic-based care for pelvic organ prolapse: protocol for the TOPSY randomised controlled trial.阴道子宫托自我管理与基于诊所的护理治疗盆腔器官脱垂的临床效果和成本效益比较:TOPSY 随机对照试验方案。
Trials. 2020 Oct 8;21(1):837. doi: 10.1186/s13063-020-04738-9.
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Factors associated with pessary fitting in women with symptomatic pelvic organ prolapse: A large prospective cohort study.
有症状盆腔器官脱垂女性中与子宫托适配相关的因素:一项大型前瞻性队列研究。
Neurourol Urodyn. 2020 Nov;39(8):2238-2245. doi: 10.1002/nau.24477. Epub 2020 Sep 16.
4
Vaginal pessary continuation in symptomatic pelvic organ prolapse patients with prior hysterectomy.阴道子宫托在有症状的盆腔器官脱垂患者中继续使用,这些患者既往有子宫切除术。
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