局部注射两性霉素 B：在真菌性上颌窦炎治疗中的新用途。
Local injection of amphotericin B: novel use in the treatment of fungal maxillary sinusitis.
机构信息
Department of Oral Medicine and Radiology, Maulana Azad Institute of Dental Sciences, New Delhi, India.
Department of Oral Medicine and Radiology, Post Graduate Institute of Dental Sciences, Rohtak, India.
出版信息
Int J Oral Maxillofac Surg. 2023 Dec;52(12):1282-1285. doi: 10.1016/j.ijom.2023.07.008. Epub 2023 Aug 5.
This report highlights the role of local amphotericin B (AMB) injection in cases of maxillary mucormycosis. The COVID-19 pandemic has resulted in a dramatic rise in the number of rhino-orbital mucormycosis cases. Although extensive surgical debridement remains the gold standard treatment, tissue salvage is desirable. The cases of two patients treated with local AMB are reported here, indicating that early intervention for maxillary fungal sinusitis in the form of local AMB may avoid the need for more invasive treatment.
本报告强调了局部两性霉素 B（AMB）注射在治疗上颌骨毛霉病中的作用。COVID-19 大流行导致了鼻眶脑毛霉病病例的急剧增加。尽管广泛的手术清创仍然是金标准治疗，但组织保存是理想的。本文报告了两例接受局部 AMB 治疗的患者，表明早期进行局部 AMB 治疗上颌真菌性鼻窦炎可能避免需要更具侵袭性的治疗。
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