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人类髋关节的基础病理决定了自我感知的疼痛和功能与临床表现之间的关系不同。

Relationships between self-perceived and clinical expression of pain and function differ based on the underlying pathology of the human hip.

机构信息

Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX, USA.

School of Medicine, Tufts University, Boston, MA, USA.

出版信息

BMC Musculoskelet Disord. 2023 Aug 7;24(1):635. doi: 10.1186/s12891-023-06768-1.

Abstract

BACKGROUND

Patient-reported outcomes are commonly used to assess patient symptoms. The effect of specific hip pathology on relationships between perceived and objectively measured symptoms remains unclear. The purpose of this study was to evaluate differences of function and pain in patients with FAIS and DDH, to assess the correlation between perceived and objective function, and to determine the influence of pain on measures of function.

METHODS

This prospective cross-sectional study included 35 pre-operative patients (60% female) with femoroacetabular impingement syndrome (FAIS) and 37 pre-operative patients (92% female) with developmental dysplasia of the hip (DDH). Objectively measured function (6-min walk [6MWT], single leg hop [SLHT], Biodex sway [BST], hip abduction strength [HABST], and STAR excursion balance reach [STAR] tests), patient-reported function (UCLA Activity, Hip Outcome Score [HOS], Short Form 12 [SF-12], and Hip Disability and Osteoarthritis Outcome Score [HOOS]), and patient-reported pain (HOOS Pain, visual analogue scale (VAS), and a pain location scale) were collected during a pre-surgical clinic visit. Between-group comparisons of patient scores were performed using Wilcoxon Rank-Sum tests. Within-group correlations were analyzed using Spearman's rank correlation coefficients. Statistical correlation strength was defined as low (r =  ± 0.1-0.3), moderate (r =  ± 0.3-0.5) and strong (r >  ± 0.5).

RESULTS

Patients with DDH reported greater pain and lower function compared to patients with FAIS. 6MWT distance was moderately-to-strongly correlated with a number of patient-reported measures of function (FAIS: r = 0.37 to 0.62, DDH: r = 0.36 to 0.55). Additionally, in patients with DDH, SLHT distance was well correlated with patient reported function (r = 0.37 to 0.60). Correlations between patient-reported pain and objectively measured function were sparse in both patient groups. In patients with FAIS, only 6MWT distance and HOOS Pain (r = -0.53) were significantly correlated. In patients with DDH, 6MWT distance was significantly correlated with VAS Average (r = -0.52) and Best (r = -0.53) pain.

CONCLUSION

Pain is greater and function is lower in patients with DDH compared to patients with FAIS. Moreover, the relationship between pain and function differs between patient groups. Understanding these differences is valuable for informing treatment decisions. We recommend these insights be incorporated within the clinical continuum of care, particularly during evaluation and selection of surgical and therapeutic interventions.

摘要

背景

患者报告的结果常用于评估患者的症状。特定髋关节病变对感知症状和客观测量症状之间关系的影响仍不清楚。本研究的目的是评估 FAIS 和 DDH 患者之间功能和疼痛的差异,评估感知功能和客观功能之间的相关性,并确定疼痛对功能测量的影响。

方法

这项前瞻性的横断面研究包括 35 名术前 FAIS 患者(60%为女性)和 37 名术前 DDH 患者(92%为女性)。客观测量的功能(6 分钟步行测试[6MWT]、单腿跳跃测试[SLHT]、Biodex 摆动测试[BST]、髋关节外展力量测试[HABST]和 STAR 伸展平衡测试[STAR])、患者报告的功能(UCLA 活动量表、髋关节结果评分[HOS]、简明健康状况调查问卷 12 项[SF-12]和髋关节残疾和骨关节炎结果评分[HOOS])以及患者报告的疼痛(HOOS 疼痛量表、视觉模拟评分[VAS]和疼痛位置量表)在术前就诊期间进行收集。使用 Wilcoxon 秩和检验对组间患者评分进行比较。使用 Spearman 秩相关系数分析组内相关性。统计相关性强度定义为低(r=±0.1-0.3)、中(r=±0.3-0.5)和高(r>±0.5)。

结果

与 FAIS 患者相比,DDH 患者报告的疼痛更严重,功能更低。6MWT 距离与多项患者报告的功能测量指标呈中度至高度相关(FAIS:r=0.37 至 0.62,DDH:r=0.36 至 0.55)。此外,在 DDH 患者中,SLHT 距离与患者报告的功能高度相关(r=0.37 至 0.60)。在两个患者组中,患者报告的疼痛与客观测量的功能之间的相关性都很稀疏。在 FAIS 患者中,只有 6MWT 距离和 HOOS 疼痛(r=-0.53)与功能显著相关。在 DDH 患者中,6MWT 距离与 VAS 平均(r=-0.52)和最佳(r=-0.53)疼痛显著相关。

结论

与 FAIS 患者相比,DDH 患者的疼痛更严重,功能更低。此外,疼痛与功能之间的关系在患者组之间存在差异。了解这些差异对于告知治疗决策很有价值。我们建议在临床护理连续体中纳入这些见解,特别是在评估和选择手术和治疗干预措施时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4de5/10405504/568e093879d7/12891_2023_6768_Fig1_HTML.jpg

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