Laboratory of Stress, Immunity, Pathogens (EA7300), Medical School, University of Lorraine, 54500, Vandoeuvre-les- Nancy, France.
CHRU Nancy, Vandoeuvre-les-Nancy, France.
Curr Neuropharmacol. 2023;21(12):2481-2486. doi: 10.2174/1570159X21666230807150523.
The effects of probiotics have mostly been shown to be favorable on measures of anxiety and stress. More recent experiments indicate single- and multi-strain probiotics in treating motorrelated diseases. Initial studies in patients with Parkinson's disease and Prader-Willi syndrome are concordant with this hypothesis. In addition, probiotics improved motor coordination in normal animals and models of Parkinson's disease, multiple sclerosis, and spinal cord injury as well as grip strength in hepatic encephalopathy. Further studies should delineate the most optimal bacterial profile under each condition.
益生菌的作用主要表现在改善焦虑和压力方面。最近的实验表明，单一菌株和多菌株益生菌都可用于治疗运动相关疾病。初步研究表明，益生菌对帕金森病和普拉德-威利综合征患者具有一定疗效，这与上述假说相符。此外，益生菌还可以改善帕金森病、多发性硬化症、脊髓损伤模型动物的运动协调性和肝性脑病患者的握力。进一步的研究应确定每种情况下最理想的细菌谱。
