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免疫功能低下患者的脑室内结核脓肿:临床病例

Intraventricular tuberculosis abscess in an immunocompromised patient: clinical vignette.

作者信息

Hanafiah Mohamad, Mukhari Shahizon A Mohamed, Mustapha Aida M, Mumin Nazimah Ab

机构信息

Department of Radiology, Sunway Medical Centre, Jalan Lagoon Selatan, Bandar Sunway, 47500 Petaling Jaya, Selangor, Malaysia.

Department of Radiology, Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia.

出版信息

Asian Biomed (Res Rev News). 2021 Dec 30;15(6):293-297. doi: 10.2478/abm-2021-0036. eCollection 2021 Dec.

Abstract

Tuberculosis is caused by . Tuberculosis of the central nervous system is common and manifestations include meningeal and intraparenchymal diseases. However, intraventricular tuberculous abscess is a rare manifestation of intracranial tuberculous infection. We present a case of an immunocompromised female patient with high-grade fever and signs of meningism. The computed tomography and magnetic resonance imaging (MRI) of the brain showed hydrocephalus with rim-enhancing lesion in the right lateral ventricle. The MRI demonstrated a hypointense signal on T1-weighted imaging, hyperintense signal on T2-weighted imaging, and mild restricted diffusion in diffusion-weighted imaging. She underwent emergency external ventricular drainage and frank pus was drained. Diagnosis of tuberculosis was made via polymerase chain reaction analysis and culture. Understanding the intracranial manifestation of neurotuberculosis is imperative to arrive at the diagnosis correctly and ensure prompt treatment.

摘要

结核病是由……引起的。中枢神经系统结核很常见,其表现包括脑膜和脑实质疾病。然而,脑室内结核脓肿是颅内结核感染的一种罕见表现。我们报告一例免疫功能低下的女性患者,有高热和脑膜刺激征。脑部计算机断层扫描和磁共振成像(MRI)显示脑积水,右侧脑室有边缘强化病变。MRI在T1加权成像上显示低信号,在T2加权成像上显示高信号,在扩散加权成像上有轻度扩散受限。她接受了紧急脑室外引流,引出了大量脓液。通过聚合酶链反应分析和培养确诊为结核病。了解神经结核的颅内表现对于正确诊断和确保及时治疗至关重要。

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