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[小下颌和喉软化新生儿的气道管理与治疗]

[The airway management and treatment of newborns with micrognathia and laryngomalacia].

作者信息

Wang Jing, Xu Mengrou, Jin Lei, Gu Meizhen, Li Xiaoyan

机构信息

Department of Otorhinolaryngology Head and Neck Surgery,Shanghai Children's Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,200062,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2023 Aug;37(8):622-625;631. doi: 10.13201/j.issn.2096-7993.2023.08.004.

Abstract

To explore the perioperative airway management and treatment of newborns with micrognathia and laryngomalacia. From January to December 2022, a total of 6 newborns with micrognathia and laryngomalacia were included. Preoperative laryngoscopy revealed concomitant laryngomalacia. These micrognathia were diagnosed as Pierre Robin sequences. All patients had grade Ⅱ or higher symptoms of laryngeal obstruction and required oxygen therapy or non-invasive ventilatory support. All patients underwent simultaneous laryngomalacia surgery and mandibular distraction osteogenesis. The shortened aryepiglottic folds were ablated using a low-temperature plasma radiofrequency during the operation. Tracheal intubation was maintained for 3-5 days postoperatively. Polysomnography(PSG) and airway CT examination were performed before and 3 months after the surgery. Among the 6 patients, 4 required oxygen therapy preoperatively and 2 required non-invasiveventilatory support. The mean age of patients was 40 days at surgery. The inferior alveolar nerve bundle was not damaged during the operation, and there were no signs of mandibular branch injury such as facial asymmetry after the surgery. Laryngomalacia presented as mixed type: type Ⅱ+ type Ⅲ. The maximum mandibular distraction distance was 20 mm, the minimum was 12 mm, and the mean was 16 mm. The posterior airway space increased from a preoperative average of 3.5 mm to a postoperative average of 9.5 mm. The AHI decreased from a mean of 5.65 to 0.85, and the lowest oxygen saturation increased from a mean of 78% to 95%. All patients were successfully extubated after the surgery, and symptoms of laryngeal obstruction such as hypoxia and feeding difficulties disappeared. Newborns with micrognathia and laryngomalacia have multi-planar airway obstruction. Simultaneous laryngomalacia surgery and mandibular distraction osteogenesis are safe and feasible, and can effectively alleviate symptoms of laryngeal obstruction such as hypoxia and feeding difficulties, while significantly improving the appearance of micrognathia.

摘要

探讨小下颌畸形合并喉软化症新生儿的围手术期气道管理及治疗方法。2022年1月至12月,共纳入6例小下颌畸形合并喉软化症的新生儿。术前喉镜检查显示合并喉软化症。这些小下颌畸形被诊断为皮埃尔·罗宾序列征。所有患者均有Ⅱ级或更高程度的喉梗阻症状,需要吸氧治疗或无创通气支持。所有患者均同时接受喉软化症手术和下颌骨牵张成骨术。术中使用低温等离子射频消融缩短的杓会厌襞。术后气管插管维持3 - 5天。术前及术后3个月进行多导睡眠图(PSG)和气道CT检查。6例患者中,4例术前需要吸氧治疗,2例需要无创通气支持。手术时患者的平均年龄为40天。术中下牙槽神经束未受损,术后未出现面部不对称等下颌支损伤迹象。喉软化症表现为混合型:Ⅱ型 + Ⅲ型。下颌骨最大牵张距离为20 mm,最小为12 mm,平均为16 mm。后气道间隙从术前平均3.5 mm增加到术后平均9.5 mm。呼吸暂停低通气指数(AHI)从平均5.65降至0.85,最低血氧饱和度从平均78%升至95%。所有患者术后均成功拔管,缺氧、喂养困难等喉梗阻症状消失。小下颌畸形合并喉软化症的新生儿存在多平面气道梗阻。同时进行喉软化症手术和下颌骨牵张成骨术安全可行,可有效缓解缺氧、喂养困难等喉梗阻症状,同时显著改善小下颌畸形外观。

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[The airway management and treatment of newborns with micrognathia and laryngomalacia].[小下颌和喉软化新生儿的气道管理与治疗]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2023 Aug;37(8):622-625;631. doi: 10.13201/j.issn.2096-7993.2023.08.004.
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本文引用的文献

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Robin Sequence: Neonatal Mandibular Distraction.罗宾序列:新生儿下颌骨牵张术。
Clin Plast Surg. 2021 Jul;48(3):363-373. doi: 10.1016/j.cps.2021.03.005. Epub 2021 May 8.
4
[Clinical practice guidelines for the diagnosis and management of laryngomalacia in children].[儿童喉软化症诊断与管理临床实践指南]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Nov;34(11):961-965. doi: 10.13201/j.issn.2096-7993.2020.11.001.
6
[Therapeutic evaluation of modified supraglottoplasty for laryngomalacia].改良声门上成形术治疗喉软化症的疗效评估
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Nov;33(11):1072-1075;1080. doi: 10.13201/j.issn.1001-1781.2019.11.016.
8
Pierre Robin Sequence.皮埃尔·罗宾序列征
Clin Plast Surg. 2019 Apr;46(2):249-259. doi: 10.1016/j.cps.2018.11.010. Epub 2019 Feb 8.
10
Pierre Robin sequence: A comprehensive narrative review of the literature over time.皮埃尔·罗宾序列:文献随时间的综合叙述性回顾。
J Stomatol Oral Maxillofac Surg. 2018 Nov;119(5):419-428. doi: 10.1016/j.jormas.2018.05.002. Epub 2018 May 17.

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