Department of Otolaryngology, Toyohashi Municipal Hospital, Toyohashi, Japan.
Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan.
Head Neck. 2023 Oct;45(10):2533-2543. doi: 10.1002/hed.27477. Epub 2023 Aug 8.
We aimed to define the indications for sentinel lymph node biopsy (SLNB), the third option for cervical treatment in oral cancer with negative cervical lymph nodes.
The greatest depth of invasion (DOI) and long diameter (LD) of the primary site were used as exposures. SLN metastasis was considered the outcome.
In three trials conducted between 2009 and 2016, 158 patients were eligible and reassigned to this study group. The scatterplot based on the respective values of DOI and LD would eventually be divided into three sections. In cases of sections T1, T2, and T3, the proportions of SLN metastasis positivity were 21.3%, 35.3%, and 51.2%, respectively. In certain cases of T1 with 2 mm < DOI ≤ 5 mm and 8 mm < LD ≤ 20 mm, the proportion of SLN metastasis positivity was 40.9%.
SLNB-navigated or assisted neck dissection can be added as an effective procedure for N0 neck control.
我们旨在确定前哨淋巴结活检（SLNB）的适应证，这是颈部淋巴结阴性口腔癌治疗的第三种选择。
原发灶的最大浸润深度（DOI）和长径（LD）被用作暴露因素。将 SLN 转移视为结局。
在 2009 年至 2016 年进行的三项试验中，有 158 名患者符合条件并被重新分配到该研究组。基于 DOI 和 LD 的相应值的散点图最终将被分为三个部分。在 T1、T2 和 T3 节中，SLN 转移阳性率分别为 21.3%、35.3%和 51.2%。在某些 DOI 为 2mm≤5mm 且 LD 为 8mm≤20mm 的 T1 病例中，SLN 转移阳性率为 40.9%。
SLNB 引导或辅助颈部解剖术可作为 N0 颈部控制的有效手段。
