Roy Pragyan
College of Basic Sciences and Humanities, OUAT, Bhubaneswar, India.
J Cancer Res Clin Oncol. 2023 Nov;149(15):14409-14427. doi: 10.1007/s00432-023-05215-x. Epub 2023 Aug 8.
Breast cancer management for young Indian women are full of challenges. The National Cancer Registry Programme (NCRP) has predicted that nearly 2,30,000 cases of breast cancer will be reported annually by 2025; with a steady increase in cases of young women (< 45 years of age) with breast cancer. In this review, the available literature is evaluated to understand the various risk factors contributing to the rise in cases of breast cancer in young women in India. Further, the challenges that are faced by the technicians in early diagnosis (e.g., physiology of young breasts, limited trained professionals, and awareness among patients, and cost of the treatment) of breast cancer. This review also focuses on the upcoming diagnostics like serum biomarkers and nanosensors for the early identification of the disease. For better prognosis and to reduce the chances of disease reoccurrence and metastasis, it is important that the disease has to be identified at an early stage.
印度年轻女性的乳腺癌治疗充满挑战。国家癌症登记计划(NCRP)预测,到2025年,每年将报告近23万例乳腺癌病例;其中年轻女性(<45岁)患乳腺癌的病例数呈稳步上升趋势。在本综述中,对现有文献进行评估,以了解导致印度年轻女性乳腺癌病例数上升的各种风险因素。此外,还探讨了技术人员在乳腺癌早期诊断中面临的挑战(例如,年轻乳房的生理特征、专业培训人员有限、患者的认知度以及治疗费用)。本综述还关注血清生物标志物和纳米传感器等新兴诊断技术,以实现疾病的早期识别。为了获得更好的预后并降低疾病复发和转移的几率,在疾病早期进行识别非常重要。