Real-World Insights, IQVIA.
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Secretaría de Salud.
Arch Cardiol Mex. 2023;93(3):328-335. doi: 10.24875/ACM.22000195.
To estimate the direct and indirect economic burden of hypercholesterolemia in patients with high risk of a cardiovascular event, specifically there were defined 5 groups of patients: 1) familial hypercholesterolemia; 2, 3 and 4) patients with hypercholesterolemia and background of diabetes, myocardial infarction or stroke; 5) diabetes, myocardial infarction and hypercholesterolemia (very high-risk patients) from the Mexican public healthcare institutions.
For the estimation of the direct costs the items included correspond to: outpatient care, pharmacological treatment, inpatient hospital care, and surgical procedures. For indirect economic burden, death certificates, before the end of the productive age due to hypercholesterolemia were calculated (premature mortality).
The direct economic burden for the 5 groups of patients at risk is MXN $39,601,464,154 (USD $1,987,526,432), while the indirect economic burden amounts to MXN $121,646,689 (USD $6,105,229).
The economic impact of hypercholesterolemia in patients with high cardiovascular risk is $39,723,110,843 (equivalent to USD $1,993,631,661) and corresponds to the 0.16% of GDP.
估计心血管事件高危患者高胆固醇血症的直接和间接经济负担，具体定义了 5 组患者：1）家族性高胆固醇血症；2、3 和 4）患有高胆固醇血症和糖尿病、心肌梗死或中风背景的患者；5）糖尿病、心肌梗死和高胆固醇血症（极高危患者）来自墨西哥公共医疗机构。
为了估计直接成本，包括门诊护理、药物治疗、住院医院护理和手术程序。对于间接经济负担，计算了因高胆固醇血症而在生产年龄结束前死亡的死亡证明（过早死亡）。
5 组高危患者的直接经济负担为 39601464154 比索（1987526432 美元），而间接经济负担为 121646689 比索（6105229 美元）。
高心血管风险患者高胆固醇血症的经济影响为 39723110843 比索（相当于 1993631661 美元），占 GDP 的 0.16%。
