Schosheim P M, Caspari R B
Arthroscopy. 1986;2(2):71-6. doi: 10.1016/s0749-8063(86)80015-9.
Recently, electrosurgical cutting instruments utilizing radiofrequency energy have been designed as arthroscopic devices for cutting meniscal tissue. This study attempted to determine the in vivo gross and microscopic effects of radiofrequency energy on meniscal tissue in rabbits. Twelve adult New Zealand white rabbits (48 menisci) underwent bilateral knee arthrotomies. Ten rabbits (40 menisci) underwent partial meniscectomies in which one half of each meniscus in the longitudinal plane was removed with the electrosurgical generator. Two control rabbits underwent arthrotomy without resection of meniscal tissue. At specific time intervals, the rabbits were killed, and the menisci were removed. The gross specimens were photographed, and microscopic sections of each meniscus were fixed and stained. Specimens were evaluated to determine the cellular and vascular response to the electrosurgical cut edge of each meniscus. The microscopic specimens revealed that the radiofrequency cutting instruments produced a small degree of direct thermal damage to the cut meniscus. A tissue response producing a hypercellular dense collagen matrix was present for approximately 3 months. The spontaneous repair of tissue was complete by 6 months, and the histologic 6-month specimens could not be distinguished from the 6-month control specimens except with respect to the overall width of the specimens.
最近，利用射频能量的电外科切割器械已被设计为用于切割半月板组织的关节镜设备。本研究试图确定射频能量对兔半月板组织的体内大体和微观影响。12只成年新西兰白兔（48个半月板）接受了双侧膝关节切开术。10只兔子（40个半月板）接受了部分半月板切除术，其中每个半月板在纵向上的一半用高频电刀切除。两只对照兔接受了不切除半月板组织的关节切开术。在特定时间间隔，处死兔子并取出半月板。对大体标本进行拍照，对每个半月板的微观切片进行固定和染色。对标本进行评估，以确定每个半月板的电外科切割边缘的细胞和血管反应。微观标本显示，射频切割器械对切割的半月板产生了一定程度的直接热损伤。产生高细胞致密胶原基质的组织反应持续约3个月。组织的自发修复在6个月时完成，除了标本的整体宽度外，6个月组织学标本与6个月对照标本无法区分。
