Department of Cardiology, Wanzhou First People Hospital, Wanzhou, Chongqing, China.
Department of Ophthalmology and Otorhinolaryngology, Wanzhou First People Hospital, Wanzhou, Chongqing, China.
J Coll Physicians Surg Pak. 2023 Aug;33(8):915-918. doi: 10.29271/jcpsp.2023.08.915.
Hypertension (HTN) is not recognised as an independent risk factor for primary open-angle glaucoma (POAG). A search of PubMed, Embase, Medline, Wanfang, and Cochrane Library databases from the time each database was established up to July 2022 was performed. All studies were pooled and assessed for heterogeneity and the quality of the literature. Five cross-sectional studies were included in the meta-analysis with 1144 individuals with POAG and 29, 373 without POAG. The combined analysis found that the incidence of HTN was higher among the individuals with POAG than among those without (OR 1.55; p <0.001). There was also a significant difference in the incidence of diabetes among individuals with POAG compared with those without (OR: 1.31; p=0.002). A meta-analysis of cross-sectional studies revealed that the incidence of HTN and diabetes was significantly greater among individuals with POAG. HTN and diabetes were found to be independent risk factors for POAG. Key Words: Primary open-angle glaucoma (POAG), Hypertension (HTN), Diabetes, Meta-analysis.
高血压（HTN）不被认为是原发性开角型青光眼（POAG）的独立危险因素。对从每个数据库建立到 2022 年 7 月的 PubMed、Embase、Medline、万方和 Cochrane Library 数据库进行了检索。对所有研究进行了汇总，并评估了异质性和文献质量。纳入了五项横断面研究，共纳入 1144 名 POAG 患者和 29373 名非 POAG 患者。合并分析发现 POAG 患者的 HTN 发病率高于非 POAG 患者（OR 1.55；p<0.001）。POAG 患者的糖尿病发病率与非 POAG 患者相比也存在显著差异（OR：1.31；p=0.002）。对横断面研究的荟萃分析显示，POAG 患者的 HTN 和糖尿病发病率显著更高。HTN 和糖尿病被认为是 POAG 的独立危险因素。关键词：原发性开角型青光眼（POAG）、高血压（HTN）、糖尿病、荟萃分析。
