Université de Lyon, INSA Lyon, CNRS, MAP UMR 5240, Villeurbanne, France.
Institut Laue-Langevin, Grenoble, France.
Soft Matter. 2023 Aug 23;19(33):6280-6286. doi: 10.1039/d3sm00352c.
Apolar lipids within the membranes of archaea are thought to play a role in membrane regulation. In this work we explore the effect of the apolar lipid squalane on the dynamics of a model archaeal-like membrane, under pressure, using neutron spin echo spectroscopy. To the best of our knowledge, this is the first report on membrane dynamics at high pressure using NSE spectroscopy. Increasing pressure leads to an increase in membrane rigidity, in agreement with other techniques. The presence of squalane in the membrane results in a stiffer membrane supporting its role as a membrane regulator.
在古菌的膜内，非极性脂质被认为在膜调节中发挥作用。在这项工作中，我们使用中子自旋回波光谱法研究了非极性脂质角鲨烷对模型古菌样膜在压力下的动力学的影响。据我们所知，这是使用 NSE 光谱法在高压下研究膜动力学的首次报道。随着压力的增加，膜的刚性增加，这与其他技术的结果一致。角鲨烷存在于膜中会导致膜更硬，这支持了它作为膜调节剂的作用。
