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大气压变化对肺栓塞发展的影响:8 年数据的回顾性分析。

Effect of atmospheric pressure changes on the development of pulmonary embolism: a retrospective analysis of 8 years of data.

机构信息

From the Department of Pulmonary Diseases, Ataturk University, Erzurum, Turkey.

From the Department of Pulmonary Diseases, Erzurum Regional Training and Research Hospital, Ezerum, Turkey.

出版信息

Ann Saudi Med. 2023 Jul-Aug;43(4):204-212. doi: 10.5144/0256-4947.2023.204. Epub 2023 Aug 3.

Abstract

BACKGROUND

Pulmonary embolism (PE) is a condition with high mortality, and determining its etiology is as important as its treatment. There are limited studies in the literature examining the effect of atmospheric pressure (AP) change on PE.

OBJECTIVES

Analyze the effect of AP level and the change in AP level on the development of PE according to year, season and months.

DESIGN

Retrospective SETTING: Department of tertiary care center PATIENTS AND METHODS: Patients with diagnosed or presumed PE who were followed up in the Erzurum Atatürk University Medicine Chest Diseases Clinic between 2012 and 2020 (8 years) were retrospectively screened for inclusion in the study by examining hospital records. Daily AP values were obtained electronically through official correspondence with the Erzurum Regional Meteorological Directorate. Patients diagnosed with PE were recorded using the hospital database and anamnesis forms. The dates of admission to hospital were recorded. Risk factors leading to the development of PE were identified using the records.

MAIN OUTCOME MEASURES

Relationship between AP values and the incidence of PE.

SAMPLE SIZE

592 RESULTS: AP, AP, and AP were significantly lower on days with PE cases compared to days without PE cases (<.001 for all). ΔAP, ΔAP, and ΔAP values were all negative on days with PE, but only the difference in ΔAP was significant (=.04).

CONCLUSIONS

This study showed that lower AP values were significantly associated with the incidence of PE. In particular, a drop in AP compared to the previous day seemed to be most associated with PE development.

LIMITATIONS

Retrospective design and only applicable to region.

CONFLICT OF INTEREST

None.

摘要

背景

肺栓塞(PE)是一种死亡率较高的疾病,确定其病因与治疗同样重要。目前,关于大气压(AP)变化对 PE 影响的研究有限。

目的

根据年份、季节和月份分析 AP 水平和 AP 水平变化对 PE 发展的影响。

设计

回顾性

设置

三级保健中心的医学胸腔疾病诊所

患者和方法

通过检查医院记录,回顾性筛选 2012 年至 2020 年(8 年)期间在 Erzurum Atatürk 大学医学胸腔疾病诊所接受随访的确诊或疑似 PE 患者,以将其纳入研究。通过与 Erzurum 地区气象局的官方通信,以电子方式获得每日 AP 值。使用医院数据库和病史表格记录 PE 患者的诊断。记录患者住院日期。使用记录确定导致 PE 发展的危险因素。

主要观察指标

AP 值与 PE 发病率之间的关系。

样本量

592

结果

与无 PE 病例的日子相比,PE 病例日的 AP、AP 和 AP 值显著较低(所有<.001)。PE 病例日的 ΔAP、ΔAP 和 ΔAP 值均为负值,但只有 ΔAP 的差异具有统计学意义(=.04)。

结论

本研究表明,较低的 AP 值与 PE 的发生显著相关。特别是与前一天相比,AP 的下降似乎与 PE 发展的相关性最大。

局限性

回顾性设计,仅适用于该地区。

利益冲突

无。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9462/10716832/7712d2b29721/0256-4947.2023.204-fig1.jpg

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