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以孤立性多发性颅神经病变为表现的原发性中枢神经系统淋巴瘤：1例极其罕见的病例。

Primary Central Nervous System Lymphoma Presenting as Isolated Multiple Cranial Neuropathies: An Extremely Rare Case.

作者信息

Lobban Geoffrey B, Luke Alex J, Basta Peter, Laziuk Katsiaryna, Kalra Amandeep, Kulhari Ashish

机构信息

Department of Neurology, University of Missouri-Kansas City, Kansas City, USA.

Department of Neurosurgery, Research Medical Center, Kansas City, USA.

出版信息

Cureus. 2023 Jul 8;15(7):e41561. doi: 10.7759/cureus.41561. eCollection 2023 Jul.

DOI:10.7759/cureus.41561
PMID:37554597
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10405868/
Abstract

Primary central nervous system lymphoma (PCNSL) is an uncommon malignancy of B-cell origin that typically involves the brain, eyes, and spinal cord without systemic spread. PCNSL typically involves the cerebral hemispheres, basal ganglia, or periventricular region. Isolated leptomeningeal PCNSL without any evidence of parenchymal involvement is very rare. We present a very unusual case of PCNSL presenting as persistent bilateral Bell's palsy and trigeminal neuralgia with magnetic resonance imaging (MRI) brain showing significantly hypertrophied enhancing bilateral facial and trigeminal nerves.

摘要

原发性中枢神经系统淋巴瘤（PCNSL）是一种罕见的B细胞起源恶性肿瘤，通常累及脑、眼和脊髓，无全身扩散。PCNSL通常累及大脑半球、基底神经节或脑室周围区域。孤立性软脑膜PCNSL且无任何实质受累证据非常罕见。我们报告一例非常不寻常的PCNSL病例，表现为持续性双侧贝尔麻痹和三叉神经痛，脑部磁共振成像（MRI）显示双侧面神经和三叉神经显著肥大并强化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd3d/10405868/57597adcb125/cureus-0015-00000041561-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd3d/10405868/cf994563448f/cureus-0015-00000041561-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd3d/10405868/7fd6e4668898/cureus-0015-00000041561-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd3d/10405868/0c9bebb29578/cureus-0015-00000041561-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd3d/10405868/57597adcb125/cureus-0015-00000041561-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd3d/10405868/cf994563448f/cureus-0015-00000041561-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd3d/10405868/7fd6e4668898/cureus-0015-00000041561-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd3d/10405868/0c9bebb29578/cureus-0015-00000041561-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd3d/10405868/57597adcb125/cureus-0015-00000041561-i04.jpg

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