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新诊断心脏结节病中应用皮质类固醇治疗而非植入装置管理短暂性高度房室传导阻滞的恢复:一例报告

Recovery of Transient High-Grade Atrioventricular Block Managed With Corticosteroid Therapy Without Device Implantation in Newly Diagnosed Cardiac Sarcoidosis: A Case Report.

作者信息

Rathore Azeem, Mgbemena Okechukwu, Adrover Lopez Pedro, Suryanarayana Prakash, Catanzaro John N, Keim Stephen

机构信息

Internal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.

Cardiology, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.

出版信息

Cureus. 2023 Jul 6;15(7):e41481. doi: 10.7759/cureus.41481. eCollection 2023 Jul.

Abstract

Atrioventricular blocks (AVBs) presenting in cardiac sarcoidosis (CS) remain an ongoing challenge for clinicians. While most initiate immunosuppressive therapy with the goal of pursuing device implantation, there is some ambiguity as to which patient cohorts actually benefit from device therapy. We present a case of a 39-year-old African American male with a past medical history of hypertension and no prior cardiac history who presented with substernal chest pain in the setting of a hypertensive emergency. He was later diagnosed with cardiac sarcoidosis by cardiac magnetic resonance imaging. His hospital course was complicated by transient Mobitz II atrioventricular block. He was started on prednisone, and while initially scheduled for an implantable cardioverter-defibrillator (ICD), his conduction block recovered. Through a multidisciplinary approach, the patient was discharged on medical management with outpatient follow-up. Since his initial hospitalization, the patient has not had any concerning cardiovascular events over the past year and has not been treated with device therapy. Our case illustrates the feasibility of effectively managing patients with cardiac sarcoidosis presenting with transient atrioventricular blocks only with corticosteroid therapy without needing device implantation.

摘要

心脏结节病(CS)中出现的房室传导阻滞(AVB)对临床医生来说仍然是一个持续存在的挑战。虽然大多数患者开始进行免疫抑制治疗,目的是为了植入心脏装置,但对于哪些患者群体真正能从装置治疗中获益仍存在一些不确定性。我们报告一例39岁非裔美国男性病例,其既往有高血压病史,无心脏病史,因高血压急症出现胸骨后胸痛。他后来通过心脏磁共振成像被诊断为心脏结节病。他的住院过程因短暂的莫氏Ⅱ型房室传导阻滞而复杂化。他开始使用泼尼松治疗,最初计划植入植入式心脏复律除颤器(ICD),但他的传导阻滞恢复了。通过多学科方法,患者出院后接受药物治疗并进行门诊随访。自首次住院以来,患者在过去一年中没有发生任何令人担忧的心血管事件,也未接受装置治疗。我们的病例说明了仅用皮质类固醇治疗有效管理心脏结节病伴短暂房室传导阻滞患者而无需植入装置的可行性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5714/10405635/b3063bc9aacd/cureus-0015-00000041481-i01.jpg

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