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测试新型Y-Z磁性肝门静脉阻断带可行性的初步动物实验。

Primary animal experiment to test the feasibility of a novel Y-Z magnetic hepatic portal blocking band.

作者信息

Zhang Miao-Miao, Li Chen-Guang, Xu Shu-Qin, Mao Jian-Qi, Ren Yu-Xiang, Zhang Yu-Han, Ma Jia, Shi Ai-Hua, Lyu Yi, Yan Xiao-Peng

机构信息

Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China.

National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China.

出版信息

World J Gastrointest Surg. 2023 Jul 27;15(7):1286-1293. doi: 10.4240/wjgs.v15.i7.1286.

Abstract

BACKGROUND

Hepatic portal blood flow occlusion is a common technique for reducing hepatic hemorrhage during hepatectomy. We designed a novel Y-Z magnetic hepatic portal blocking band (Y-Z MHPBB) based on the principle of magnetic compression technique.

AIM

To introduce the Y-Z MHPBB device and verify the feasibility of this device for hepatic portal blood flow occlusion in dogs.

METHODS

Ten beagles were randomly divided into the experimental group and control group. The operation time, intraoperative blood loss, the number of portal blood flow occlusions, the total time spent on adjusting the blocking band, and the average time spent on adjusting the blocking band were recorded. The surgeons evaluated the feasibility and flexibility of the two portal occlusion devices.

RESULTS

Laparoscopic hepatectomy was successfully performed in both the experimental group and control group. There was no statistical difference between the two groups in the operation time, intraoperative blood loss, and the number of hepatic portal blood flow occlusions. With respect to the total time spent on adjusting the blocking band and the average time spent on adjusting the blocking band, the experimental group showed significantly better outcomes than the control group, with a statistical difference ( < 0.05). The operators found that the Y-Z MHPBB was superior to the modified T-tube in terms of operational flexibility.

CONCLUSION

The Y-Z MHPBB seems to be an ingenious design, accurate blood flow occlusion effect, and good flexibility; and it can be used for hepatic portal blood flow occlusion during laparoscopic hepatectomy.

摘要

背景

肝门静脉血流阻断是肝切除术中减少肝出血的常用技术。我们基于磁压缩技术原理设计了一种新型的Y-Z型磁性肝门静脉阻断带(Y-Z MHPBB)。

目的

介绍Y-Z MHPBB装置并验证该装置在犬肝门静脉血流阻断中的可行性。

方法

将10只比格犬随机分为实验组和对照组。记录手术时间、术中出血量、门静脉血流阻断次数、调整阻断带总时间以及调整阻断带平均时间。外科医生评估两种门静脉阻断装置的可行性和灵活性。

结果

实验组和对照组均成功实施了腹腔镜肝切除术。两组在手术时间、术中出血量和肝门静脉血流阻断次数方面无统计学差异。在调整阻断带总时间和调整阻断带平均时间方面,实验组的结果明显优于对照组,差异有统计学意义(<0.05)。操作者发现Y-Z MHPBB在操作灵活性方面优于改良T形管。

结论

Y-Z MHPBB设计巧妙,血流阻断效果准确,灵活性好;可用于腹腔镜肝切除术中肝门静脉血流阻断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef12/10405127/ed3afa5ec744/WJGS-15-1286-g001.jpg

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